Results 101 to 110 of about 1,279,869 (296)

Combining the Attribute Oriented Induction and Graph Visualization to Enhancement Association Rules Interpretation

open access: yesIraqi Journal for Computers and Informatics, 2016
The important methods of data mining is large and from these methods is mining of association rule. The mining of association rule gives huge number of the rules.
Safaa Al-Mamory, Zahraa Abdullah
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Skeletal images as visual cues in graph visualization [PDF]

open access: yes, 1998
The problem of graph layout and drawing is fundamental to many aproaches to the visualization of relational information structures. As the data set grows, the visualization problem is compounded by the need to reconcile the user's need for orientation ...
Melançon, G.   +13 more
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Medoid-based shadow value validation and visualization

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics), 2019
A silhouette index is a well-known measure of an internal criteria validation for the clustering algorithm results. While it is a medoid-based validation index, a centroid-based validation index that is called a centroid-based shadow value (CSV) has been
Weksi Budiaji
doaj   +1 more source

Graph Visualization: Alternative Models Inspired by Bioinformatics. [PDF]

open access: yesSensors (Basel), 2023
Kolomeets M   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Using adjacency matrices to lay out larger small-world networks [PDF]

open access: yes, 2016
Many networks exhibit small-world properties. The structure of a small-world network is characterized by short average path lengths and high clustering coefficients.
Vickers, Paul, Gibson, Helen
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Force-Directed Immersive 3D Network Visualization

open access: yesComputers
Network visualization, in mathematics often referred to as graph visualization, has evolved significantly over time, offering various methods to effectively represent complex data structures.
Alexander Brezani   +2 more
doaj   +1 more source

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