Results 101 to 110 of about 258,118 (263)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Graph visualization in space and time

, 2015
Die visuelle Analyse von Graphen umfasst eine Vielzahl verschiedener Aspekte (Struktur, Attribute, räumlicher und zeitlicher Bezug). Aufgrund der steigenden Größe dieser Graphen und eines während der Analyse wechselnden Fokus wird deren Darstellung immer problematischer und bedingt eine Unzahl verschiedener Visualisierungen.
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Semi-Supervised Learning for Multi-View Data Classification and Visualization

Information
Data visualization has several advantages, such as representing vast amounts of data and visually demonstrating patterns within it. Manifold learning methods help us estimate lower-dimensional representations of data, thereby enabling more effective ...
Najmeh Ziraki, Alireza Bosaghzadeh, Fadi Dornaika   +2 more
doaj   +1 more source

Visual Navigation of Compound Graphs [PDF]

, 2005
This paper describes a local update scheme for the algorithm of Sugiyama and Misue (IEEE Trans. on Systems, Man, and Cybernetics 21 (1991) 876–892) for drawing views of compound graphs. A view is an abstract representation of a compound graph; it is generated by contracting subgraphs into meta nodes.
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

On Kamada-Kawai graph layout with graph neural networks

Радіоелектронні і комп'ютерні системи
Traditional force-directed layout algorithms, such as the Kamada-Kawai (KK) method, are widely used for graph visualization due to their ability to produce aesthetically pleasing layouts.
Olena Linnyk, Lyudmyla Polyakova, Iryna Zaretska   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Software system for simulation of study of queuing system with heterogeneous servers and independent queues

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013
Software package for simulation of study and automated visualization of the state orgraph of queuing system with heterogeneous servers and independent limited queues is described. The base of the algorithm is the method of description of such queues with
Andrey P Kotenko, Maksim B Bukarenko
doaj