Results 101 to 110 of about 1,279,869 (296)
The important methods of data mining is large and from these methods is mining of association rule. The mining of association rule gives huge number of the rules.
Safaa Al-Mamory, Zahraa Abdullah
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Skeletal images as visual cues in graph visualization [PDF]
The problem of graph layout and drawing is fundamental to many aproaches to the visualization of relational information structures. As the data set grows, the visualization problem is compounded by the need to reconcile the user's need for orientation ...
Melançon, G. +13 more
core +2 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Medoid-based shadow value validation and visualization
A silhouette index is a well-known measure of an internal criteria validation for the clustering algorithm results. While it is a medoid-based validation index, a centroid-based validation index that is called a centroid-based shadow value (CSV) has been
Weksi Budiaji
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Graph Visualization: Alternative Models Inspired by Bioinformatics. [PDF]
Kolomeets M +3 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Using adjacency matrices to lay out larger small-world networks [PDF]
Many networks exhibit small-world properties. The structure of a small-world network is characterized by short average path lengths and high clustering coefficients.
Vickers, Paul, Gibson, Helen
core +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Force-Directed Immersive 3D Network Visualization
Network visualization, in mathematics often referred to as graph visualization, has evolved significantly over time, offering various methods to effectively represent complex data structures.
Alexander Brezani +2 more
doaj +1 more source

