Results 101 to 110 of about 267,239 (309)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Visualization-Panel for Provenance Data
, 2008 Today’s IT-systems are becoming more difficult. Their relationship together grows as well as their complexity. Currently a main requirement is for people to trust more in the results and have a better understanding of the functionality.
Kunde, Markus
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
An object-oriented design for graph visualization [PDF]
, 2000 Many applications, from everyday file system browsers to visual programming tools, require the display of network and graph structures. The Graph Visualization Framework (GVF) is an architecture that supports the tasks common to most graph browsers and ...
Herman, Ivan +4 more
core
Graph Visualization: Alternative Models Inspired by Bioinformatics. [PDF]
Sensors (Basel), 2023 Kolomeets M +3 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
An overview of interactive visual data mining techniques for knowledge discovery [PDF]
, 2013 n the past decade, the analysis of data has faced the challenge of dealing with very large and complex datasets and the real-time generation of data. Technologies to store and access these complex and large datasets are in place.
Gaber, Mohamed Medhat +11 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
From Databases to Graph Visualization
2010 14th International Conference Information Visualisation, 2010 The first step of any information visualization system is to enable end user to import their dataset into the system. However, non expert user are faced to the difficult task of choosing how their data should/could be transform to be used in these Infovis systems.
Gilbert, Frédéric, Auber, David
openaire +3 more sources