Results 61 to 70 of about 258,118 (263)
Medoid-based shadow value validation and visualization
A silhouette index is a well-known measure of an internal criteria validation for the clustering algorithm results. While it is a medoid-based validation index, a centroid-based validation index that is called a centroid-based shadow value (CSV) has been
Weksi Budiaji
doaj +1 more source
Integrative study of Arabidopsis thaliana metabolomic and transcriptomic data with the interactive MarVis-Graph software [PDF]
State of the art high-throughput technologies allow comprehensive experimental studies of organism metabolism and induce the need for a convenient presentation of large heterogeneous datasets.
Manuel Landesfeind +6 more
doaj +2 more sources
Visualization of Parallel Execution Graphs [PDF]
Measuring and evaluating the runtime of parallel programs is a difficult task. In this paper we present tools for performance evaluation and visualization in the distributed thread system (DTS), a programming environment for portable parallel applications.
Björn Steckelbach +5 more
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The important methods of data mining is large and from these methods is mining of association rule. The mining of association rule gives huge number of the rules.
Safaa Al-Mamory, Zahraa Abdullah
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Graphs Drawn With Some Vertices per Face: Density and Relationships
Graph drawing beyond planarity is a research area that has received an increasing attention in the last twenty years, driven by the necessity to mitigate the visual complexity inherent in geometric representations of non-planar graphs. This research area
Carla Binucci +8 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
GRAPH VISUALIZATION OF TRACEROUTE UTILITY RESULTS FOR COMPUTER NETWORK ANALYSIS
Background. Monitoring destination reachability, path discovery, and latency analysis is essential for network performance, reliability, and security.
Ivan Danych +2 more
doaj +1 more source

