Results 61 to 70 of about 200,163 (265)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Diamond raw detection system based on machine vision

open access: yesJin'gangshi yu moliao moju gongcheng, 2019
In order to reduce the detection cost and avoid human error, a diamond rough detection system based on machine vision is developed. The information of size, shape and color of diamond is detected by image processing, and a three-dimensional model of ...
SHI Guangfeng   +4 more
doaj  

METHODS OF LEARNING IN PROCESS OF SPORTS TRAINING [PDF]

open access: yesSport Mont, 2006
Methods of learning the sports problems mean the appropriate technique of management with process, which makes possible getting the optimal technique of sports development and theoretical understanding of sports technique, successively adding adding new,
Duško Bjelica
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Effects of the Floating Action Button on Quality of Experience

open access: yesFuture Internet, 2019
Google’s Material Design, created in 2014, led to the extended application of floating action buttons (FAB) in user interfaces of web pages and mobile applications.
Jesenka Pibernik   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Sustainable Banking Practices: Impact, challenges and opportunities [PDF]

open access: yesE3S Web of Conferences
Sustainable banking practices have increased prominently in the recent times as financial institutions realises the importance of integrating ESGs into their businesses.
Sharma Shruti   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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