Results 51 to 60 of about 2,609,461 (289)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A/effective Bodies: A Review of Eszter Szép’s Comics and The Body: Drawing, Reading, and Vulnerability (2020)

open access: yesThe Comics Grid: Journal of Comics Scholarship, 2021
This review offers a critical overview of Eszter Szép’s Comics and The Body: Drawing, Reading, and Vulnerability (2020), a text that formulates a model of embodied interpretation and creation that establishes a dialogue between reader and artist based on
Andrew Godfrey-Meers
doaj   +2 more sources

The Reception of Translated and Adapted Texts on Disease Prevention for Pre-Adolescents Using Graphic Medicine Strategies

open access: yesMutatis Mutandis
In recent years, the links between Translation Studies and Graphic Medicine have strengthened to enhance the dissemination of specialized health information for lay audiences.
Antonio Hermán-Carvajal
doaj   +1 more source

A Map of the Current Cultural Climate in Medicine and Healthcare, and How We Can Change It

open access: yesThe Comics Grid: Journal of Comics Scholarship, 2022
In Canada, healthcare and medicine are grounded in structures of coloniality, oppression, heteropatriarchy and a variety of “-isms” (racism, sexism, ableism, classism). Consequently, it is little wonder that deep-rooted, enduring health disparities exist
Savita Rani
doaj   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

La ‘graphic medicine’: curarsi con i comics

open access: yesGriseldaonline, 2019
The doctor-patient relationship and the improvement of the patients’ health conditions through storytelling multiple forms, from cinema to digital diaries, is the current research issue of the narrative medicine.
Stefano Calabrese
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

“Can’t We Talk About Something More Pleasant”

open access: yesVoices in Bioethics, 2014
End of life issues don’t always have to be so difficult to discuss, especially upon reading New Yorker cartoonist Roz Chast’s new memoir, “Can’t We Talk About Something More Pleasant.” Now spending its eighth week at the top of The New York Times best ...
Randi Belisomo
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy