Results 31 to 40 of about 53,305 (257)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Representing and Visualizing Archaeology. The Contribution of Graphic Sciences to Research in Archaeology

open access: yesimg journal
This article discusses the role of images in archaeological disciplines and the contribution that graphic sciences can make to research in this subject area.
Enrico Cicalò, Michele Valentino
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

HOW TO ACHIEVE A GRAPHIC LANGUAGE IN A SIGNAGE SYSTEM

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
This paper presents the importance of a signage system to inform and guide with a purpose: to make useful an activity. It is a special role of graphics to connect people to a system which has to be clear and legible. Along our researches in this field we
ADÎR Victor   +2 more
doaj  

“El Plato del Bien Comer”, ¿evidencia científica o conocimiento transpuesto?

open access: yesCPU-e, 2015
El artículo analiza los contenidos conceptuales, procedimentales y valorales de las Normas Oficiales Mexicanas NOM-015-SSA2-2010 “Para la prevención, tratamiento y control de la diabetes mellitus” y NOM-043-SSA2-2012 “Servicios Básicos de Salud ...
Mtro. Juan Manuel Muñoz Cano
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Construção e reconstrução de um sistema hipermídia sobre anticorpos monoclonais com base na estrutura cognitiva do especialista de conteúdo Building and rebuilding of a hipermidia system based on the teaching/specialist content's cognitive structure: a case study on monoclonal antibodies system

open access: yesCiência & Educação, 2006
Relata-se o desenvolvimento do sistema hipermídia Anticorpos Monoclonais, com desenho baseado no conhecimento estrutural de um especialista de conteúdo.
Miriam Struchiner   +2 more
doaj   +1 more source

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