Results 41 to 50 of about 67,416 (348)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Graphic representation of data [PDF]

open access: yes, 2006
Questions, comments or suggestions about this model may be sent to Dr. Leigh Little, llittle@brockport.edu, The College at Brockport.To introduce students to TI-84 technology To show graphic representation of dataSUNY ...
Bush, Bonnie
core  

Representing and Visualizing Archaeology. The Contribution of Graphic Sciences to Research in Archaeology

open access: yesimg journal
This article discusses the role of images in archaeological disciplines and the contribution that graphic sciences can make to research in this subject area.
Enrico Cicalò, Michele Valentino
doaj   +1 more source

“El Plato del Bien Comer”, ¿evidencia científica o conocimiento transpuesto?

open access: yesCPU-e, 2015
El artículo analiza los contenidos conceptuales, procedimentales y valorales de las Normas Oficiales Mexicanas NOM-015-SSA2-2010 “Para la prevención, tratamiento y control de la diabetes mellitus” y NOM-043-SSA2-2012 “Servicios Básicos de Salud ...
Mtro. Juan Manuel Muñoz Cano
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Perception of Representation in Visual Graphic Language

open access: yes, 2017
This paper addresses an interesting field of communication, namely visual graphic language. The principles of this special communication language (visual graphic language) are presented in a case study that highlights graphic visual perception of the ...
Laura Ivascu
core   +1 more source

Construção e reconstrução de um sistema hipermídia sobre anticorpos monoclonais com base na estrutura cognitiva do especialista de conteúdo Building and rebuilding of a hipermidia system based on the teaching/specialist content's cognitive structure: a case study on monoclonal antibodies system

open access: yesCiência & Educação, 2006
Relata-se o desenvolvimento do sistema hipermídia Anticorpos Monoclonais, com desenho baseado no conhecimento estrutural de um especialista de conteúdo.
Miriam Struchiner   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

HOW TO ACHIEVE A GRAPHIC LANGUAGE IN A SIGNAGE SYSTEM

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
This paper presents the importance of a signage system to inform and guide with a purpose: to make useful an activity. It is a special role of graphics to connect people to a system which has to be clear and legible. Along our researches in this field we
ADÎR Victor   +2 more
doaj  

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