Results 51 to 60 of about 55,461 (257)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Graphic styles for the representation of the landscape.

open access: yesDisegnare con, 2019
 Long before the landscaper existed as we understand it now, the study of landscape was already a great concern for society, tackled by cartographers and artists.
Marina Sender Contell   +1 more
doaj  

Peat, Actor and Design Tool

open access: yesSpool
This essay explores integrating experimental graphic methods into the design process to engage with more-than-human worlds. It is based on the graduation project ‘RE-Peat: Different Futures for the Peat Polders, a Social-Ecological Landscape in the ...
Anastasiia Soshnikova, Inge Bobbink
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

On the representations of string pairs over virtual field

open access: yes四川大学学报. 自然科学版
Let 𝔽1 be the virtual field consisting of one element and Q,I a string pair.In this paper, we study the representations of string pairs over the virtual field 𝔽1.It is proved that an indecomposable 𝔽1-representation is either a string representation or a
TAO Kun, FU Chang-Jian
doaj  

The Systematisation of Survey Drawings: Identifying the Development of Morphological Awareness via Teaching Approaches

open access: yesBuildings
The graphic replication of architectural examples has long been a prevalent pedagogical method, regardless of educational orientation. The critical reactivity of the mid-20th century, reinforced by ethnographic and anthropological tools, positioned ...
Gilberto Duarte Carlos, Alejandro López
doaj   +1 more source

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