Results 81 to 90 of about 3,718,583 (296)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

typo/graphic days 8

open access: yes, 2023
Typo/graphic days is an annual event of lectures and workshops on typography and graphic design organised by the The Semiotics and Visual Communication Lab (SVC Lab) of the Department of Multimedia and Graphic Arts, the Language and Graphic Communication
Panayides, Angelos
core  

Positive decreasing solutions of systems of second order singular differential equations

open access: yesJournal of Inequalities and Applications, 2000
Singular differential systems of the type are considered in an interval , where , , , are positive constants and , , , are positive continuous functions on .
Kusano Takaŝi, Tanigawa Tomoyuki
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Disorder in Student Union Building, 1964

open access: yes, 1964
Students left the Student Union Building in disarray on June 18, 1964 at Pacific University.[Back] Photo By The Photo Graphic Forest Grove, Oregon Phone ELgin 7-3117 Please use Number 1888-5 When ...
The Photo Graphic Forest Grove, Oregon, photographer
core   +1 more source

On Two Iterative Methods for Mixed Monotone Variational Inequalities

open access: yesFixed Point Theory and Applications, 2010
A mixed monotone variational inequality (MMVI) problem in a Hilbert space is formulated to find a point such that for all , where is a monotone operator and is a proper, convex, and lower semicontinuous function on . Iterative algorithms are
Xu Hong-Kun, Lu Xiwen, Yin Ximing
doaj  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

On the Solution of the Rational Matrix Equation

open access: yesEURASIP Journal on Advances in Signal Processing, 2007
We study numerical methods for finding the maximal symmetric positive definite solution of the nonlinear matrix equation , where is symmetric positive definite and is nonsingular.
Faßbender Heike, Benner Peter
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Obstacle Problem for the -Harmonic Equation

open access: yesJournal of Inequalities and Applications, 2010
Firstly, we define an order for differential forms. Secondly, we also define the supersolution and subsolution of the -harmonic equation and the obstacle problems for differential forms which satisfy the -harmonic equation, and we obtain the relations
Bao Gejun, Zhu Haijing, Cao Zhenhua
doaj  

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