Results 141 to 150 of about 48,970 (328)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Graphical Comparison of Screening Designs using Support Recovery Probabilities [PDF]

open access: green, 2023
Kade Young   +4 more
openalex   +1 more source

Counterfactual graphical models for longitudinal mediation analysis with unobserved confounding

open access: yes, 2013
Questions concerning mediated causal effects are of great interest in psychology, cognitive science, medicine, social science, public health, and many other disciplines.
Shpitser, Ilya
core  

Optimizing pressure gradient on the MHD peristaltic blood flow of nanofluids by - response surface methodology

open access: yesResults in Control and Optimization
This study focuses on optimization of pressure gradient on MHD peristaltic nanofluid flow by response surface methodology (RSM). The governing equations, including continuity, motion, nanoparticle, and concentration force are solved by disregarding ...
Saima Muhammad   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Visual Inference and Graphical Representation in Regression Discontinuity Designs [PDF]

open access: green, 2021
Christina Korting   +4 more
openalex   +1 more source

A comparison of design and model selection methods for supersaturated experiments

open access: yes
Various design and model selection methods are available for supersatu-rated designs having more factors than runs but little research is available ontheir comparison and evaluation.
Woods, David C., Marley, Christopher J.
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

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