Results 121 to 130 of about 48,970 (328)
UI-Design driven model-based testing
, 2009 Testing interactive systems is notoriously difficult. Not only do we need to ensure that the functionality of the developed system is correct with respect to the requirements and specifications, we also need to ensure that the user interface to the ...
Reeves, Steve +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Optimal design for goodness-of-fit of the Michaelis-Menten enzyme kinetic function [PDF]
We construct efficient designs for the Michaelis-Menten enzyme kinetic model capable of checking model assumption. An extended model, called EMAX model is also considered for this purpose.
Dette, Holger +2 more
core
A Programmable Metasurface Framework With Modular Architecture for Flexible and Scalable Deployment
IEEE AccessThis work presents a programmable metasurface framework featuring a modular, tile-based architecture that decouples the control electronics from the metasurface panel. Unlike traditional monolithic designs that have challenges in terms of scalability and
Loukas Petrou +5 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
, 1992 This document presents the Graphical Extension (GE) to the EARA Model, used in the Metaview project. Similar to the EARA Model having two layers: one for describing a development method (environment) and another to describe actual designs or systems for ...
Piotr Findeisen, The Graphical
core
CONCEPTUAL PRODUCT DESIGN IN VIRTUAL PROTOTYPING
Journal of Industrial Design and Engineering Graphics, 2009 A conceptual model of the industrial design process for isolation against vibrations is proposed and described. This model can be used to design products subject to functional, manufacturing, ergonomic, aesthetic constraints.
Debeleac Carmen, Nastac Silviu
doaj
twowaytests: An R package for two-way tests in independent groups designs
SoftwareXTwo-way tests in independent groups designs are the most frequently used statistical techniques in various fields. In this paper, we present twowaytests package to investigate the effects of two treatments and the associated interaction on the dependent ...
Osman Dag +4 more
doaj +1 more source