Results 81 to 90 of about 12,459,066 (303)
The species chromatogram, a new graphical method to represent, characterize, and compare the ecological niches of different species. [PDF]
Ecol Evol, 2022 Kléparski L, Beaugrand G.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Representing WWW navigational data: a graphical methodology to support qualitative analysis
Information Research: An International Electronic Journal, 1999 This paper concerns the development and use of a graphical methodology in the analysis of individuals World Wide Web navigational behaviour. Specifically, it reports on the comparison of this methodology to other methodologies of qualitative analysis ...
Honey Lucas
doaj
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
High-Dimensional Graphical Model Search with the gRapHD R Package [PDF]
This paper presents the R package gRapHD for efficient selection of high-dimensional undirected graphical models. The package provides tools for selecting trees, forests, and decomposable models minimizing information criteria such as AIC or BIC, and for
Rodrigo Labouriau +2 more
core
Graphical method for identifying high outliers in construction contract auctions [PDF]
, 2001 Construction contract auctions are characterised by (1) a heavy emphasis on the lowest bid as that is which usually determines the winner of the auction, (2) anticipated high outliers due to the presence of uncompetitive bids, (3) very small samples, and
Skitmore, Martin
core
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Connections between single-factor analysis and graphical Gaussian models
, 2006 The classical single-factor model is parametrized as a graphical Gaussian model. The relationship between the classical parametrization of the single-factor model and this alternative parametrization is derived.
Smith, Peter W. F. +2 more
core +1 more source