Results 41 to 50 of about 151,101 (262)

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz   +7 more
wiley   +1 more source

Software for cerebrospinal fluid diagnostics and statistics

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Background: In CSF analysis for diagnostics we have knowledge-based software for numerical and graphical data interpretation, but software programs for statistics are scarce.
Hansotto Reiber
doaj  

Cumulative deviation of a subpopulation from the full population

open access: yesJournal of Big Data, 2021
Assessing equity in treatment of a subpopulation often involves assigning numerical “scores” to all individuals in the full population such that similar individuals get similar scores; matching via propensity scores or appropriate covariates is common ...
Mark Tygert
doaj   +1 more source

Evaluating the Readability of Patient‐Facing Online Educational Materials for Pediatric Leukemia and Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Together, leukemia and lymphoma account for 38.7% of newly diagnosed pediatric cancer cases in the United States each year. Many caregivers utilize online resources to inform medical health decisions. Understanding the readability of these materials is critical to ensuring comprehensible patient education.
Chloe Strege   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Application of Selected Methods and Approaches for Improvement of Processes and their Use in Practice in Companies of Wood Processing Industry in Slovakia

open access: yesManagement Systems in Production Engineering, 2019
The aim of the paper is to point out the principles of process management and selected quality management tools, which are aimed at improving the processes of the wood processing industries of the Slovak Republic.
Simanová Ľubica, Gejdoš Pavol
doaj   +1 more source

Visualising disease progression on multiple variables with vector plots and path plots

open access: yesBMC Medical Research Methodology, 2009
Background It is often desirable to observe how a disease progresses over time in individual patients, rather than graphing group averages; and since multiple outcomes are typically recorded on each patient, it would be advantageous to visualise disease ...
Michell Andrew W   +3 more
doaj   +1 more source

Modified XLindley distribution: Properties, estimation, and applications

open access: yesAIP Advances, 2023
This article aims to introduce the inverse new XLindley distribution, a further extension of the new XLindley distribution. The article explores various properties of the proposed model, such as the quantile function, stochastic orders, entropies, fuzzy ...
Ahmed M. Gemeay   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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