Results 101 to 110 of about 22,758,545 (367)
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
A Novel Approach to Deducing of the Data- PAPR Relation for OFDM System
Journal of Engineering and Sustainable Development, 2012 Orthogonal Frequency Division Multiplexing (OFDM) is a very attractive technique for high-data-rate transmission in wireless and wired applications. The main drawback of the OFDM technique is its high peak to average power ratio (PAPR).
Dhafer R. Zaghar, Tahreer Sh. Mahmoud
doaj
Graph-based multivariate conditional autoregressive models
Statistical Theory and Related Fields, 2019 The conditional autoregressive model is a routinely used statistical model for areal data that arise from, for instances, epidemiological, socio-economic or ecological studies.
Ye Liang
doaj +1 more source
Sparse Graphical Linear Dynamical Systems [PDF]
arXiv, 2023 Time-series datasets are central in machine learning with applications in numerous fields of science and engineering, such as biomedicine, Earth observation, and network analysis. Extensive research exists on state-space models (SSMs), which are powerful mathematical tools that allow for probabilistic and interpretable learning on time series. Learning
arxiv
Algebraic Aspects of Conditional Independence and Graphical Models
, 2017 This chapter of the forthcoming Handbook of Graphical Models contains an overview of basic theorems and techniques from algebraic geometry and how they can be applied to the study of conditional independence and graphical models.
Kahle, Thomas +2 more
core +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Structure Learning in Graphical Modeling [PDF]
Annual Review of Statistics and Its Application, 2017 A graphical model is a statistical model that is associated with a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models have computationally convenient factorization properties and have long been a valuable tool for tractable modeling of multivariate
Drton M., Maathuis M.H.
openaire +3 more sources
Modeling the Game of Go by Ising Hamiltonian, Deep Belief Networks and Common Fate Graphs
IEEE Access, 2019 Three different models of the game of Go are developed by establishing an analogy between this game and physical systems susceptible to analysis under the well-known Ising model in two dimensions. The Ising Hamiltonian is adapted to measure the energy of
Alfonso Rojas-Dominguez +2 more
doaj +1 more source
CanvasVAE: Learning to Generate Vector Graphic Documents [PDF]
arXiv, 2021 Vector graphic documents present visual elements in a resolution free, compact format and are often seen in creative applications. In this work, we attempt to learn a generative model of vector graphic documents. We define vector graphic documents by a multi-modal set of attributes associated to a canvas and a sequence of visual elements such as shapes,
arxiv
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source