Results 101 to 110 of about 1,268,383 (321)
Gene Networks Based on the Graphical Gaussian Model
This protocol describes how to build a gene network based on the graphical Gaussian model (GGM) from large scale microarray data. GGM uses partial correlation coefficient (pcor) to infer co-expression relationship between genes.
Shisong Ma
doaj +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The mimR Package for Graphical Modelling in R [PDF]
The mimR package for graphical modelling in R is introduced. We present some facilities of mimR, namely those relating specifying models, editing models, fitting models and doing model search.
Søren Højsgaard
core +1 more source
Knowledge Model Based on Graphical Semantic Perception
Based on knowledge representation in product design, we propose a knowledge model of the product design process based on graphical semantic perception.
Jian Liu, Haisong Huang, Weijie Pan
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Multibody dynamics model building using graphical interfaces [PDF]
In recent years, the extremely laborious task of manually deriving equations of motion for the simulation of multibody spacecraft dynamics has largely been eliminated.
Macala, Glenn A.
core +1 more source
Integrating Theoretical Components: A Graphical Model for Graduate Students and Researchers [PDF]
David M. Choate +8 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Flexible and Accurate Methods for Estimation and Inference of Gaussian Graphical Models with Applications [PDF]
Yueqi Qian, Xianghong Hu, Can Yang
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source

