Results 101 to 110 of about 22,057,993 (342)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Graphic Models of Nicknames in the German-Speaking Internet-Space
Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 2. Âzykoznanie, 2015 The object of the study is a specific anthroponymic element of the onomastic system in German – the network name (nickname) and its representation in the German section of the Internet.
Viktoriya Viktorovna Kazyaba
doaj +1 more source
Loop Calculus for Non-Binary Alphabets using Concepts from Information Geometry [PDF]
, 2014 The Bethe approximation is a well-known approximation of the partition function used in statistical physics. Recently, an equality relating the partition function and its Bethe approximation was obtained for graphical models with binary variables by ...
Mori, Ryuhei
core +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
, 2021 This thesis concerns the theory and the inference of a new class of independence models based on a graphical representation that we name profile graphs. Multiple graph models are special cases in this class and the compatibility in terms of independence structure is derived with respect to chain graph models of different types.
openaire +3 more sources
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Causal Inference Using Graphical Models with the R Package pcalg
Journal of Statistical Software, 2012 The pcalg package for R can be used for the following two purposes: Causal structure learning and estimation of causal effects from observational data.
Markus Kalisch +4 more
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