Results 111 to 120 of about 418,262 (313)

PepGM: A graphical model for taxonomic profiling of viral proteomes

open access: yes, 2021
In mass spectrometry based proteomics, protein homology leads to many shared peptides within and between species. This complicates taxonomic inference. inference.
Holstein, Tanja
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Teaching ‘Instant Experience’ with Graphical Model Validation Techniques

open access: yes, 2014
Graphical model validation techniques for linear normal models are often used to check the assumptions underlying a statistical model. We describe an approach to provide 'instant experience' in looking at a graphical model validation plot, so it becomes ...
Ekstrøm, Claus Thorn, Ekstrøm, C. T.
core   +1 more source

Graphical Multi-way Models [PDF]

open access: yes, 2010
Multivariate multi-way ANOVA-type models are the default tools for analyzing experimental data with multiple independent covariates. However, formulating standard multi-way models is not possible when the data comes from different sources or in cases where some covariates have (partly) unknown structure, such as time with unknown alignment.
Ilkka Huopaniemi   +3 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Beat Tracking the Graphical Model Way

open access: yes, 2008
We present a graphical model for beat tracking in recorded music. Using a probabilistic graphical model allows us to incorporate local information and global smoothness constraints in a principled manner.
Nando Freitas, Dustin Lang
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Graphical Model for Infant Eye Movements.

open access: yes, 2012
A graphical model for inferring the cognitive processes () responsible for generated eye movements () under particular experimental conditions (). This model adaptively groups infants into like clusters () and implements a sparsity prior to prevent ...
Shohei Hidaka (125494)   +2 more
core   +1 more source

Graphical model selection for a particular class of continuous-time processes [PDF]

open access: yes, 2019
summary:Graphical models provide an undirected graph representation of relations between the components of a random vector. In the Gaussian case such an undirected graph is used to describe conditional independence relations among such components.
Zorzi, Mattia, Zorzi Mattia
core   +1 more source

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