Results 101 to 110 of about 1,309,109 (281)
Journal of Causal InferenceI thank Thomas Richardson and James Robins for their discussion of my article, and discuss the similarities and differences between their approach to causal modelling, based on single world intervention graphs, and my own decision-theoretic approach.
Dawid Philip
doaj +1 more source
Foresight of innovative processes in the environics of production systems
π-EconomyThe article reveals such urgent problems and areas of environmentalism as modern processes of interaction between production and the environment; increasing the sustainability of the environmental impact of production processes and innovative ways of ...
Kirilchuk Svetlana, Morozova Irina
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Causal Inference Using Graphical Models with the R Package pcalg
Journal of Statistical Software, 2012 The pcalg package for R can be used for the following two purposes: Causal structure learning and estimation of causal effects from observational data.
Markus Kalisch +4 more
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Graphical models of separation logic
Information Processing Letters, 2009 Labelled graphs are used to model control and data flow among events occurring in the execution of a (possibly concurrent) program. Data flow is a unifying concept that covers both access to memory and communication along channels; it covers many variations including weakly consistent memory, re-ordered execution, and communication channels that are ...
Wehrman, I, Hoare, C, O'Hearn, P
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Gene Networks Based on the Graphical Gaussian Model
Bio-Protocol, 2012 This protocol describes how to build a gene network based on the graphical Gaussian model (GGM) from large scale microarray data. GGM uses partial correlation coefficient (pcor) to infer co-expression relationship between genes.
Shisong Ma
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Knowledge Model Based on Graphical Semantic Perception
Cybernetics and Information Technologies, 2015 Based on knowledge representation in product design, we propose a knowledge model of the product design process based on graphical semantic perception.
Jian Liu, Haisong Huang, Weijie Pan
doaj +1 more source