Results 51 to 60 of about 22,175,501 (301)

Explicit Formula of Koszul–Vinberg Characteristic Functions for a Wide Class of Regular Convex Cones

open access: yesEntropy, 2016
The Koszul–Vinberg characteristic function plays a fundamental role in the theory of convex cones. We give an explicit description of the function and related integral formulas for a new class of convex cones, including homogeneous cones and cones ...
Hideyuki Ishi
doaj   +1 more source

Graphical Presentation of the Steady-state Economy Model

open access: yesThe Journal of Population and Sustainability, 2022
There are several theories claiming that their policies can save the planet from environmental catastrophe. This paper claims that it is only the Steady-State Economy model on which such reasonably effective expectations can be based.
Theodore Lianos
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Efficient Proximal Gradient Algorithms for Joint Graphical Lasso

open access: yesEntropy, 2021
We consider learning as an undirected graphical model from sparse data. While several efficient algorithms have been proposed for graphical lasso (GL), the alternating direction method of multipliers (ADMM) is the main approach taken concerning joint ...
Jie Chen, Ryosuke Shimmura, Joe Suzuki
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Graphical Independence Networks with the gRain Package for R

open access: yesJournal of Statistical Software, 2012
In this paper we present the R package gRain for propagation in graphical independence networks (for which Bayesian networks is a special instance). The paper includes a description of the theory behind the computations.
Soren Hojsgaard
doaj  

Graph-based multivariate conditional autoregressive models

open access: yesStatistical Theory and Related Fields, 2019
The conditional autoregressive model is a routinely used statistical model for areal data that arise from, for instances, epidemiological, socio-economic or ecological studies.
Ye Liang
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bayesian Network Modeling Applied to Feline Calicivirus Infection Among Cats in Switzerland

open access: yesFrontiers in Veterinary Science, 2020
Bayesian network (BN) modeling is a rich and flexible analytical framework capable of elucidating complex veterinary epidemiological data. It is a graphical modeling technique that enables the visual presentation of multi-dimensional results while ...
Gilles Kratzer   +11 more
doaj   +1 more source

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