Results 71 to 80 of about 22,057,993 (342)
EasyModeller: A graphical interface to MODELLER [PDF]
BMC Research Notes, 2010 MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit difficult to start with MODELLER as it is command line based and requires knowledge of basic Python scripting to use it efficiently.The study was
Pallu Reddanna +2 more
openaire +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Active Learning for Undirected Graphical Model Selection [PDF]
, 2014 This paper studies graphical model selection, i.e., the problem of estimating a graph of statistical relationships among a collection of random variables.
Baraniuk, Richard G. +2 more
core +1 more source
Graphical Models for Genetic Analyses
Statistical Science, 2003 This paper introduces graphical models as a natural environment in which to formulate and solve problems in genetics and related areas. Particular emphasis is given to the relationships among various local computation algorithms which have been developed within the hitherto mostly separate areas of graphical models and genetics.
Lauritzen, S.L., Sheehan, Nuala A.
openaire +7 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Foresight of innovative processes in the environics of production systems
π-EconomyThe article reveals such urgent problems and areas of environmentalism as modern processes of interaction between production and the environment; increasing the sustainability of the environmental impact of production processes and innovative ways of ...
Kirilchuk Svetlana, Morozova Irina
doaj +1 more source
Projective Latent Dependency Forest Models
IEEE Access, 2019 Latent dependence forest models (LDFM) are a new type of probabilistic models with the advantage of not requiring the difficult procedure of structure learning in model learning.
Yong Jiang, Yang Zhou, Kewei Tu
doaj +1 more source
Stratified Gaussian graphical models [PDF]
Communications in Statistics - Theory and Methods, 2016 23 pages, 12 ...
Nyman, Henrik +2 more
openaire +4 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source