Results 41 to 50 of about 317,964 (264)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evaluating and comparing crowd simulations: Perspectives from a crowd authoring tool
Graphical ModelsCrowd simulation is a research area widely used in diverse fields, including gaming and security, assessing virtual agent movements through metrics like time to reach their goals, speed, trajectories, and densities.
Gabriel Fonseca Silva +3 more
doaj +1 more source
Two-step techniques for accurate selection of small elements in VR environments
Graphical Models, 2023 One of the key interactions in 3D environments is target acquisition, which can be challenging when targets are small or in cluttered scenes. Here, incorrect elements may be selected, leading to frustration and wasted time.
Elena Molina, Pere-Pau Vázquez
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Quasi-interpolation projectors for subdivision function spaces
Graphical ModelsSubdivision surfaces as an extension of splines have become a promising technique for addressing PDEs on models with complex topologies in isogeometric analysis.
Hailun Xu, Zepeng Wen, Hongmei Kang
doaj +1 more source
A robust workflow for b-rep generation from image masks
Graphical Models, 2023 A novel approach to generating watertight, manifold boundary representations from noisy binary image masks of MRI or CT scans is presented. The method samples an input segmented image and locally approximates the material boundary.
Omar M. Hafez, Mark M. Rashid
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
FACE: Feature-preserving CAD model surface reconstruction
Graphical ModelsFeature lines play a pivotal role in the reconstruction of CAD models. Currently, there is a lack of a robust explicit reconstruction algorithm capable of achieving sharp feature reconstruction in point clouds with noise and non-uniformity. In this paper,
Shuxian Cai +3 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Topological Modeling for Vector Graphics [PDF]
IEEE Computer Graphics and Applications, 2019 In recent years, with the development of mobile phones, tablets, and web technologies, we have seen an ever-increasing need to generate vector graphics content, that is, resolution-independent images that support sharp rendering across all devices, as well as interactivity and animation.
Boris Dalstein, James D. Foley
openaire +2 more sources