Results 61 to 70 of about 325,747 (265)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Visual simulation of fruit chilling injury

open access: yesGraphical Models
Chilling injury (CI) is a major postharvest physiological disorder in fruits, causing quality degradation and economic losses during low-temperature storage.
Yixin Xu, Shiguang Liu
doaj   +1 more source

Probabilistic Graphical Models [PDF]

open access: yes, 2014
This report presents probabilistic graphical models that are based on imprecise probabilities using a simplified language. In particular the discussion is focused on credal networks and discrete domains. It describes the building blocks of credal networks algorithms to perform inference and discusses on complexity results and related work.
Antonucci, Alessandro   +2 more
openaire   +1 more source

Graphical models of separation logic

open access: yesInformation Processing Letters, 2009
Labelled graphs are used to model control and data flow among events occurring in the execution of a (possibly concurrent) program. Data flow is a unifying concept that covers both access to memory and communication along channels; it covers many variations including weakly consistent memory, re-ordered execution, and communication channels that are ...
Wehrman, I, Hoare, C, O'Hearn, P
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Improving the area-preserving parameterization of rational Bézier surfaces by rational bilinear transformation

open access: yesGraphical Models
To improve the area-preserving parameterization quality of rational Bézier surfaces, an optimization algorithm using bilinear reparameterization is proposed.
Xiaowei Li   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

DISCO: Efficient Diffusion Solver for large-scale Combinatorial Optimization problems

open access: yesGraphical Models
Combinatorial Optimization (CO) problems are fundamentally important in numerous real-world applications across diverse industries, notably computer graphics, characterized by entailing enormous solution space and demanding time-sensitive response ...
Hang Zhao   +5 more
doaj   +1 more source

Graphical Multi-way Models [PDF]

open access: yes, 2010
Multivariate multi-way ANOVA-type models are the default tools for analyzing experimental data with multiple independent covariates. However, formulating standard multi-way models is not possible when the data comes from different sources or in cases where some covariates have (partly) unknown structure, such as time with unknown alignment.
Ilkka Huopaniemi   +3 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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