Results 61 to 70 of about 1,036,354 (257)

3DMeshNet: A three-dimensional differential neural network for structured mesh generation

Graphical Models
Mesh generation is a crucial step in numerical simulations, significantly impacting simulation accuracy and efficiency. However, generating meshes remains time-consuming and requires expensive computational resources.
Jiaming Peng, Xinhai Chen, Jie Liu
doaj   +1 more source

Algebraic Methods of Classifying Directed Graphical Models

, 2014
Directed acyclic graphical models (DAGs) are often used to describe common structural properties in a family of probability distributions. This paper addresses the question of classifying DAGs up to an isomorphism.
Polyanskiy, Yury, Roozbehani, Hajir
core   +1 more source

Stratified Gaussian graphical models [PDF]

Communications in Statistics - Theory and Methods, 2016
23 pages, 12 ...
Nyman, Henrik, Pensar, Johan, Corander, Jukka   +2 more
openaire   +3 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Efficient extraction of experimental data from line charts using advanced machine learning techniques

Graphical Models
Line charts, as a common data visualization tool in scientific research and business analysis, encapsulate rich experimental data. However, existing data extraction tools face challenges such as low automation levels and difficulties in handling complex ...
Wenjin Yang, Jie He, Xiaotong Zhang
doaj   +1 more source

Loop Calculus for Non-Binary Alphabets using Concepts from Information Geometry [PDF]

, 2014
The Bethe approximation is a well-known approximation of the partition function used in statistical physics. Recently, an equality relating the partition function and its Bethe approximation was obtained for graphical models with binary variables by ...
Mori, Ryuhei
core   +1 more source

High Dimensional Semiparametric Gaussian Copula Graphical Models

, 2012
In this paper, we propose a semiparametric approach, named nonparanormal skeptic, for efficiently and robustly estimating high dimensional undirected graphical models.
Han, Fang, Lafferty, John, Liu, Han, Wasserman, Larry, Yuan, Ming   +4 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

CADTrans: A code tree-guided CAD generative transformer model with regularized discrete codebooks

Graphical Models
The creation of computational agents capable of generating computer-aided design (CAD) models that rival those produced by professional designers is a pressing challenge in the field of computational design.
Xufei Guo, Xiao Dong, Juan Cao, Zhonggui Chen   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source