Results 111 to 120 of about 303,097 (314)
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Graphics calculators: A (brief) case of technology
Undergraduate service courses in mathematics are not generally regarded as providing fertile ground for experimentation, and nor are they usually sought after as stimulating educational environments. perhaps inaccurately on both counts.
Kissane, B., Bradley, J., Kemp, M.
core
Visualising the scene: computer graphics and evidence presentation
In the UK forensic animations are becoming an increasingly important visual aid in courtroom situations, where complex data relating to a sequence of events is being visualised before a general public who may have little or no understanding of ...
Schofield, Damian +3 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Графика Зинаиды Серебряковой и Елизаветы Кругликовой в собрании Белгородского художественного музея
Статья посвящена изучению восьми графических произведений Зинаиды Серебряковой и оттиска Елизаветы Кругликовой из собрания Белгородского государственного художественного музея. Эти произведения вводятся в научный оборот впервые.
Селютина, А.А.
doaj +1 more source
Generating explanatory captions for information graphics
Graphical presentations can be used to communicate information in relational data sets succinctly and effectively. However, novel graphical presentations about numerous attributes and their relationships are often difficult to understand completely until
Moore, Johanna D. +8 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

