Results 51 to 60 of about 201,580 (310)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Utility-based performance evaluation of biometric sample quality measures

EURASIP Journal on Image and Video Processing
The quality score of a biometric sample is intended to predict the sample’s degree of utility for biometric recognition. Different authors proposed different definitions for utility.
Olaf Henniger, Biying Fu, Alexander Kurz
doaj   +1 more source

«Книга Ангелов» Андрея Машанова

Искусство Евразии, 2019
В статье рассматривается авторская книга – «Книга Ангелов» Андрея Машанова, заслуженного художника России, известного сибирского графика, мастера офорта и каллиграфии. Подчеркивается, что книга выполняется в жанре книга художника (Livre d’artiste, Artist’
Гуменюк, Алла Николаевна
doaj   +1 more source

Graphics for Uncertainty [PDF]

Journal of the Royal Statistical Society Series A: Statistics in Society, 2019
SummaryGraphical methods such as colour shading and animation, which are widely available, can be very effective in communicating uncertainty. In particular, the idea of a ‘density strip’ provides a conceptually simple representation of a distribution and this is explored in a variety of settings, including a comparison of means, regression and models ...
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Образ и личность. Человек в cтанковой графике Натальи Бакановой-Вейберт

Искусство Евразии, 2019
В статье рассматривается биография и творчество нашей современницы, художницы Н.Л. Бакановой (в девичестве Вейберт), имеющей немецкое происхождение и прекрасное образование в лучших традициях русско-советской художественной школы.
Королева, Анастасия Юрьевна
doaj   +1 more source

Graphics in Early Childhood Education

Konteksty Pedagogiczne, 2020
The article presents the assumptions and results of a natural pedagogical quasi-experiment which was carried out with children in grades 1–3 of primary school.
Urszula Szuścik
doaj   +1 more source

Accelerating High-Dimensional Temporal Modelling Using Graphics Processing Units for Pharmacovigilance Signal Detection on Real-Life Data [PDF]

, 2022
Pierre Sabatier, Jean Feydy, Anne‐Sophie Jannot   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source