Results 81 to 90 of about 36,410 (306)

From computation to environmental cost the resource burden of artificial intelligence

open access: yesCommunications Earth & Environment
Here we quantify the material footprint of artificial intelligence training by linking computational workloads to physical hardware needs. Graphics processing unit demand is expressed as equivalent hardware lifetime consumed and, thus, the material ...
Sophia Falk   +4 more
doaj   +1 more source

Symmetric Tridiagonal Eigenvalue Solver Across CPU Graphics Processing Unit (GPU) Nodes

open access: yesApplied Sciences
In this work, an improved and scalable implementation of Cuppen’s algorithm for diagonalizing symmetric tridiagonal matrices is presented. This approach uses a hybrid-heterogeneous parallelization technique, taking advantage of GPU and CPU in a ...
Erika Hernández-Rubio   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Mesh–particle interpolations on graphics processing units and multicore central processing units

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2011
Particle–mesh interpolations are fundamental operations for particle-in-cell codes, as implemented in vortex methods, plasma dynamics and electrostatics simulations. In these simulations, the mesh is used to solve the field equations and the gradients of the fields are used in order to advance the particles.
Rossinelli D, Conti C, Koumoutsakos P
openaire   +3 more sources

Discrete wavelet transform on consumer-level graphics processing unit

open access: yes, 2008
The discrete wavelet transform (DWT) has been extensively studied and developed in various scientific and engineering fields. The multiresolution and local nature of the DWT facilitates applications requiring progressiveness and the capture of high ...
Xu, Zhijie   +3 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A Framework for Megascale Agent Based Model Simulations on Graphics Processing Units [PDF]

open access: yes
Agent-based modeling is a technique for modeling dynamic systems from the bottom up. Individual elements of the system are represented computationally as agents.
Roshan M. D'Souza, Mikola Lysenko
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Calculation of Force Field Grids for Molecular Docking Using Graphics Processing Unit [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2014
The vast majority of problems faced by bioinformatics are very complex and time consuming. They require the use of modern high-performance computational systems and the development of algorithms for such system.
Mikhail A. Farkov
doaj  

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