Results 61 to 70 of about 31,009 (260)

Research on Big Data Application for Security

Dianxin kexue, 2015
Several data sources of big data on security were described，a closer look was taken at the implementation of big data platform on security，the main points and steps during the implementation were also proposed.Specially，detail analysis on the overall ...
Deli Yang, Tao Zhang
doaj   +2 more sources

Exploring Graphics Processing Unit (GPU) Resource Sharing Efficiency for High Performance Computing

Computers, 2013
The increasing incorporation of Graphics Processing Units (GPUs) as accelerators has been one of the forefront High Performance Computing (HPC) trends and provides unprecedented performance; however, the prevalent adoption of the Single-Program Multiple ...
Teng Li, Vikram K. Narayana, Tarek El-Ghazawi   +2 more
doaj   +1 more source

Accelerating Forward Algorithm for Stochastic Automata on Graphics Processing Units

IEEE Access, 2020
A stochastic automaton is a non-deterministic automata with input and output behavior which works serially and synchronously. Stochastic automata is being used in different application areas.
Muhammad Umer Sarwar, Muhammad Kashif Hanif, Ramzan Talib, Muhammad Haris Aziz   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

From computation to environmental cost the resource burden of artificial intelligence

Communications Earth & Environment
Here we quantify the material footprint of artificial intelligence training by linking computational workloads to physical hardware needs. Graphics processing unit demand is expressed as equivalent hardware lifetime consumed and, thus, the material ...
Sophia Falk, Nicholas Kluge Corrêa, Sasha Luccioni, Lisa Biber-Freudenberger, Aimee van Wynsberghe   +4 more
doaj   +1 more source

Symmetric Tridiagonal Eigenvalue Solver Across CPU Graphics Processing Unit (GPU) Nodes

Applied Sciences
In this work, an improved and scalable implementation of Cuppen’s algorithm for diagonalizing symmetric tridiagonal matrices is presented. This approach uses a hybrid-heterogeneous parallelization technique, taking advantage of GPU and CPU in a ...
Erika Hernández-Rubio, Alberto Estrella-Cruz, Amilcar Meneses-Viveros, Jorge Alberto Rivera-Rivera, Liliana Ibeth Barbosa-Santillán, Sergio Víctor Chapa-Vergara   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source