Results 41 to 50 of about 32,874 (261)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Simulation of the linear mechanical oscillator on GPU [PDF]
FME Transactions, 2014 In this short paper we are describing some methods for solving stochastic differential equations which appears in mechanics. We are concerned with solutions of mechanical oscillators which are subject to random excitation.
Cvetković Aleksandar +2 more
doaj
Accelerating Computer-Based Recognition of Fynbos Leaves Using a Graphics Processing Unit
South African Computer Journal, 2017 The Cape Floristic Kingdom (CFK) is the most diverse floristic kingdom in the world and has been declared an international heritage site. However, it is under threat from wild fires and invasive species. Much of the work of managing this natural resource,
Simon Lucas Winberg +2 more
doaj +1 more source
Pseudo-depth domain reverse time migration in VTI medium based on GPU parallel strategy
Frontiers in Earth Science, 2023 As one of the main imaging methods, a lot of attention has been directed to reverse time migration anisotropic media. However, reverse time migration still faces cost and memory limitations, especially in imaging high frequencies.
Zhang Xinwen +7 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Grace: A cross-platform micromagnetic simulator on graphics processing units
SoftwareX, 2015 A micromagnetic simulator running on graphics processing units (GPUs) is presented. Different from GPU implementations of other research groups which are predominantly running on NVidia’s CUDA platform, this simulator is developed with C++ Accelerated ...
Ru Zhu
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Evaluation of NVIDIA Xavier NX Platform for Real-Time Image Processing for Plasma Diagnostics
Energies, 2022 Machine protection is a core task of real-time image diagnostics aiming for steady-state operation in nuclear fusion devices. The paper evaluates the applicability of the newest low-power NVIDIA Jetson Xavier NX platform for image plasma diagnostics ...
Bartłomiej Jabłoński +8 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source