Results 51 to 60 of about 32,874 (261)
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Evaluating Power and Energy Efficiency of Bitonic Mergesort on Graphics Processing Unit
IEEE Access, 2017 Excessive power consumption is expected to be the major obstacle to achieve exascale performance within a reasonable power budget in the upcoming years. In addition, graphics processing units (GPUs) are expected to become a significant ingredient in the ...
Muhammad Abdulhamid Al-Hashimi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Research on Big Data Application for Security
Dianxin kexue, 2015 Several data sources of big data on security were described，a closer look was taken at the implementation of big data platform on security，the main points and steps during the implementation were also proposed.Specially，detail analysis on the overall ...
Deli Yang, Tao Zhang
doaj +2 more sources
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
From computation to environmental cost the resource burden of artificial intelligence
Communications Earth & EnvironmentHere we quantify the material footprint of artificial intelligence training by linking computational workloads to physical hardware needs. Graphics processing unit demand is expressed as equivalent hardware lifetime consumed and, thus, the material ...
Sophia Falk +4 more
doaj +1 more source
Symmetric Tridiagonal Eigenvalue Solver Across CPU Graphics Processing Unit (GPU) Nodes
Applied SciencesIn this work, an improved and scalable implementation of Cuppen’s algorithm for diagonalizing symmetric tridiagonal matrices is presented. This approach uses a hybrid-heterogeneous parallelization technique, taking advantage of GPU and CPU in a ...
Erika Hernández-Rubio +5 more
doaj +1 more source
A graphics processing unit-accelerated meshless method for two-dimensional compressible flows
Engineering Applications of Computational Fluid Mechanics, 2017 A graphics processing unit (GPU) -accelerated meshless method is presented for solving two-dimensional compressible flows over aerodynamic bodies. The Compute Unified Device Architecture (CUDA) Fortran programming model is employed to port the meshless ...
Jiale Zhang, Hongquan Chen, Cheng Cao
doaj +1 more source