Results 181 to 190 of about 5,075,844 (278)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Feature-PLPD-Aided Visual-Inertial Odometry for Low-Cost Embedded Systems. [PDF]

Sensors (Basel)
Mamri A, El Hadri A, Benallegue A, Hachicha K.   +3 more
europepmc   +1 more source

Baselining Large Language Model Performance in Systems Engineering Using SysEngBench

Systems Engineering, EarlyView.
ABSTRACT In the rapidly evolving field of artificial intelligence (AI), large language model s (LLMs) have demonstrated impressive capabilities in generating natural language. However, their proficiency in specialized domains, particularly in the field of systems engineering (SE), remains less explored and unquantified.
Ryan Bell, Ryan Longshore, Raymond Madachy, Ashlyn Hanrahan   +3 more
wiley   +1 more source

Green AI architectures: Navigating the security-sustainability paradox in critical infrastructure protection. [PDF]

Environ Sci Ecotechnol
Lee J, Tayerani Charmchi AS, Ghobadi F, Kim MI.   +3 more
europepmc   +1 more source

A Spatio‐Temporal Dynamics Model for Indoor Environmental Forecasting

IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
Accurate forecasting of indoor environmental conditions is essential for intelligent building operations and comfort‐oriented controls. However, reliable prediction remains challenging due to spatial heterogeneity across sensing locations, complex multi‐modal interactions, and nonstationary temporal dynamics.
Goro Terumichi, Jiarui Li, Tatsuji Kimura, Hiroaki Nishi   +3 more
wiley   +1 more source

GeNePi: a graphics processing unit enhanced next-generation bioinformatics pipeline for whole-genome sequencing analysis. [PDF]

Brief Bioinform
Marangoni S, Furia F, Charrance D, Fant A, Di Dio S, Trova S, Spirito G, Musacchia F, Coppe A, Gustincich S, Vecchi M, Landuzzi F, Cavalli A.   +12 more
europepmc   +1 more source

Reflections on the Future of Statistics Education in a Technological Era

Teaching Statistics, EarlyView.
ABSTRACT Keeping pace with rapidly evolving technology is a key challenge in teaching statistics. To equip students with essential skills for the modern workplace, educators must integrate relevant technologies into the statistical curriculum where possible.
Craig Alexander, Jennifer Gaskell, Vinny Davies   +2 more
wiley   +1 more source

Accelerated long-read variant calling with Clair3 for whole-genome sequencing. [PDF]

Bioinformatics
Zheng Z, He M, Yu X, Li J, Chen L, Wong AOK, Zhang J, Zhou Y, Luo R.   +8 more
europepmc   +1 more source

starU‐Net: An enhanced U‐Net architecture with star operation and multi‐view fusion for improved vessel segmentation

VIEW, EarlyView.
Low‐contrast capillaries are often missed or fragmented by segmentation models, so we developed a shallow four‐level starU‐Net that combines star operation‐based feature extraction with dynamic snake convolution‐based multi‐view fusion for improved thin vessel continuity.
Mengwei Bai, Li Tong, Jing Lin, Peng Huang   +3 more
wiley   +1 more source

Direct Reconstruction of High-Fidelity Electrocardiogram Signals From Vector-Based PDF Files With Integrated Deep Learning for Multiparameter Estimation: Retrospective Methodological Study. [PDF]

JMIR Form Res
Shie SS, Huang PY, Wen MS, Wang CY.
europepmc   +1 more source