Results 61 to 70 of about 233,815 (328)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

ASAMgpu V1.0 – a moist fully compressible atmospheric model using graphics processing units (GPUs) [PDF]

open access: yesGeoscientific Model Development, 2012
In this work the three dimensional compressible moist atmospheric model ASAMgpu is presented. The calculations are done using graphics processing units (GPUs).
S. Horn
doaj   +1 more source

Optimizing UniFrac with OpenACC Yields Greater Than One Thousand Times Speed Increase

open access: yesmSystems, 2022
UniFrac is an important tool in microbiome research that is used for phylogenetically comparing microbiome profiles to one another (beta diversity).
Igor Sfiligoi   +4 more
doaj   +1 more source

Fast Calculation of the Lomb-Scargle Periodogram Using Graphics Processing Units

open access: yes, 2010
I introduce a new code for fast calculation of the Lomb-Scargle periodogram, that leverages the computing power of graphics processing units (GPUs). After establishing a background to the newly emergent field of GPU computing, I discuss the code design ...
Aubert   +14 more
core   +1 more source

An Optimized Parallel IDCT on Graphics Processing Units [PDF]

open access: yes, 2013
In this paper we present an implementation of the H.264/AVC Inverse Discrete Cosine Transform (IDCT) optimized for Graphics Processing Units (GPUs) using OpenCL.
Chi, Chi Ching   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Fluid-film lubrication computing with many-core processors and graphics processing units

open access: yesAdvances in Mechanical Engineering, 2018
The advancement of modern processors with many-core and large-cache may have little computational advantages if only serial computing is employed. In this study, several parallel computing approaches, using devices with multiple or many processor cores ...
Nenzi Wang, Hsin-Yi Chen, Yu-Wen Chen
doaj   +1 more source

Compressed Multi-Row Storage Format for Sparse Matrices on Graphics Processing Units

open access: yes, 2014
A new format for storing sparse matrices is proposed for efficient sparse matrix-vector (SpMV) product calculation on modern graphics processing units (GPUs).
Koza, Zbigniew   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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