Results 81 to 90 of about 233,815 (328)

Automatic parallelization for graphics processing units [PDF]

Proceedings of the 7th International Conference on Principles and Practice of Programming in Java, 2009
Accelerated graphics cards, or Graphics Processing Units (GPUs), have become ubiquitous in recent years. On the right kinds of problems, GPUs greatly surpass CPUs in terms of raw performance. However, because they are difficult to program, GPUs are used only for a narrow class of special-purpose applications; the raw processing power made available by ...
Alan Leung, Ondřej Lhoták, Ghulam Lashari   +2 more
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

GPU-BSM: a GPU-based tool to map bisulfite-treated reads. [PDF]

PLoS ONE, 2014
Cytosine DNA methylation is an epigenetic mark implicated in several biological processes. Bisulfite treatment of DNA is acknowledged as the gold standard technique to study methylation.
Andrea Manconi, Alessandro Orro, Emanuele Manca, Giuliano Armano, Luciano Milanesi   +4 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Accelerated JPEG Decompression on Graphics Processing Units [PDF]

, 2014
Tato práce řeší problematiku dekomprese JPEG, návrh algoritmů pro provedení dekomprese na grafické kartě a jejich implementaci. Podrobněji se pak zabývá konkrétním postupem implementace včetně možných alternativ a optimalizací.
Janošík, Ondřej
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Direct numerical simulation of compressible turbulence accelerated by graphics processing unit. Part 1: An open-source high accuracy accelerated computational fluid dynamic software [PDF]

, 2022
Guanlin Dang, Shiwei Liu, Tongbiao Guo, Junyi Duan, Xinliang Li   +4 more
openalex   +1 more source

Pipelined Iterative Solvers with Kernel Fusion for Graphics Processing Units

, 2016
We revisit the implementation of iterative solvers on discrete graphics processing units and demonstrate the benefit of implementations using extensive kernel fusion for pipelined formulations over conventional implementations of classical formulations ...
Grasser, Tibor, Jüngel, Ansgar, Rupp, Karl, Weinbub, Josef   +3 more
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source