Results 31 to 40 of about 591,094 (354)

Bayesian graphical models for software testing [PDF]

IEEE Transactions on Software Engineering, 2002
This paper describes a new approach to the problem of software testing. The approach is based on Bayesian graphical models and presents formal mechanisms for the logical structuring of the software testing problem, the probabilistic and statistical treatment of the uncertainties to be addressed, the test design and analysis process, and the ...
Wooff, D. A., Goldstein, M., Coolen, F. P. A.   +2 more
openaire   +3 more sources

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

FEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang, Meritxell Wu‐Lu, Alberto Collauto, Peter‐Leon Hagedoorn, Madalina Alexandru, Maike Henschel, Shahram Kordasti, Maria Andrea Mroginski, Maxie M. Roessler, Kourosh H. Ebrahimi   +9 more
wiley   +1 more source

Research on quantitative performance model of GPU graphics processing based on unified rendering architecture

Dianzi Jishu Yingyong, 2019
The unified rendering architecture GPU provides a rich graphics computing and storage resources and puts forward higher requirements for software optimization.
Ma Chengcheng, Tian Ze, Li Xiaoyu, Sun Linna   +3 more
doaj   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source

SysMap: A Lightweight Software Visualization Tool to Analyze the Software Evolution of a System [PDF]

arXiv, 2021
Software visualization helps to comprehend the system by providing a vivid illustration. The developers, as well as the analysts, can have a glance over the total system to understand the basic changes over time from a high-level point of view through this technique.
arxiv  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

YENİ GRAFİK UYGULAMA GELİŞTİRME ARAYÜZLERİNİN KARŞILAŞTIRILMASI

Pamukkale University Journal of Engineering Sciences, 2003
Bu makalede grafik yazılımları geliştirmede kullanılan uygulama geliştirme arayüzleri sınıflandırılarak kısaca tanıtılmıştır. İki boyutlu ve üç boyutlu uygulama geliştirme arayüzlerinin özellikleri belirtilmiştir.
Aybars Uğur, Mustafa Türksever
doaj   +2 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Automatic Modification of Steel House Drawings by Finite Element Software for Coal Yard in Power Plant

发电技术, 2018
In order to reduce environmental effect by open coal yard in power plant, coal yard in power plants is required to be transformed into a closed space. The closed transformation of the coal yard adopts a large steel structure.
Zhengxin LI, Liangliang DING, Yinping HAO, Dongmei DU   +3 more
doaj   +1 more source