Results 31 to 40 of about 576,949 (348)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Perprof-py: A Python Package for Performance Profile of Mathematical Optimization Software

Journal of Open Research Software, 2016
A very important area of research in the field of Mathematical Optimization is the benchmarking of optimization packages to compare solvers. During benchmarking, one usually collects a large amount of information like CPU time, number of functions ...
Abel Soares Siqueira, Raniere Gaia Costa da Silva, Luiz-Rafael Santos   +2 more
doaj   +1 more source

Interacting with the biomolecular solvent accessible surface via a haptic feedback device [PDF]

, 2009
Background: From the 1950s computer based renderings of molecules have been produced to aid researchers in their understanding of biomolecular structure and function.
Hayward, Steven, Laycock, Stephen D., Stocks, Matthew B.   +2 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Automatic Modification of Steel House Drawings by Finite Element Software for Coal Yard in Power Plant

发电技术, 2018
In order to reduce environmental effect by open coal yard in power plant, coal yard in power plants is required to be transformed into a closed space. The closed transformation of the coal yard adopts a large steel structure.
Zhengxin LI, Liangliang DING, Yinping HAO, Dongmei DU   +3 more
doaj   +1 more source

التعليم الإلکترونى ودوره فى فن الجرافيک بکليات الفنون الجميلة لمواکبة تکنولوجيا العصر [PDF]

Journal of Distance Learning and Open Learning, 2014
Search provides a vision of the importance of e-learning and its objectives and its features and benefits , and their strategies as well as Arab and international experiences that have to go to be applied in different educational environments experience ...
أحمد أحمد
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Approximate Bayesian Image Interpretation using Generative Probabilistic Graphics Programs [PDF]

, 2013
The idea of computer vision as the Bayesian inverse problem to computer graphics has a long history and an appealing elegance, but it has proved difficult to directly implement.
Kulkarni, Tejas D., Mansinghka, Vikash K., Perov, Yura N., Tenenbaum, Joshua B.   +3 more
core   +4 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

CREATING AN INFORMATIONAL WEBSITE FOR PHYSICS ACADEMIC COURSE: WEB DESIGN SPECIFICS

Інформаційні технології і засоби навчання, 2017
The article is devoted to the analysis of means and methods of creating an educational informational website for the Physics academic course. The stages of technical task creation, design of the main and typical pages of the website, layout, programming,
Іryna A. Slipukhina, Taras V. Gedenach, Vyacheslav V. Olkhovyk   +2 more
doaj