Results 31 to 40 of about 2,907,251 (335)

SEURAT: Visual analytics for the integrated analysis of microarray data

BMC Medical Genomics, 2010
Background In translational cancer research, gene expression data is collected together with clinical data and genomic data arising from other chip based high throughput technologies.
Bullinger Lars, Döhner Konstanze, Rücker Frank, Lück Sonja, Sill Martin, Gribov Alexander, Benner Axel, Unwin Antony   +7 more
doaj   +1 more source

ACCPlot: gráficos del ACP con Mathematica

Revista de Matemática: Teoría y Aplicaciones, 2009
ACPPlot is a command for creating graphics for Principal Component Analysis (PCA), principal planes and correlation circles; in both cases, adding options for joining points with trajectories, clustering points, labeling and for improving the general ...
Carlos Arce Salas
doaj   +1 more source

Research on quantitative performance model of GPU graphics processing based on unified rendering architecture

Dianzi Jishu Yingyong, 2019
The unified rendering architecture GPU provides a rich graphics computing and storage resources and puts forward higher requirements for software optimization.
Ma Chengcheng, Tian Ze, Li Xiaoyu, Sun Linna   +3 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Bayesian graphical models for software testing [PDF]

IEEE Transactions on Software Engineering, 2002
This paper describes a new approach to the problem of software testing. The approach is based on Bayesian graphical models and presents formal mechanisms for the logical structuring of the software testing problem, the probabilistic and statistical treatment of the uncertainties to be addressed, the test design and analysis process, and the ...
Wooff, D. A., Goldstein, M., Coolen, F. P. A.   +2 more
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Automatic Modification of Steel House Drawings by Finite Element Software for Coal Yard in Power Plant

发电技术, 2018
In order to reduce environmental effect by open coal yard in power plant, coal yard in power plants is required to be transformed into a closed space. The closed transformation of the coal yard adopts a large steel structure.
Zhengxin LI, Liangliang DING, Yinping HAO, Dongmei DU   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source