Results 51 to 60 of about 3,567,179 (304)
Visualising software in cyberspace [PDF]
, 1999 The problems of maintaining software systems are well documented. The increasing size and complexity of modern software serves only to worsen matters.
Young, Peter
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
A prototype for configuring hardware and software
, 2022 S.303-310A prototype for configuring hardware and software was developed during a project among IBM Lehre und Forschung, the Computer Graphics Center (ZGDV), and the Institute for Interactive Computer Graphics (GRIS) from TH Darmstadt. It aims at helping
Messina, A. +4 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
molVisual3D: A standalone executable software for 3D visualization of molecules [PDF]
Network BiologyIn this article, a standalone executable software molVisual3D, for 3D visualization of molecules was developed. It uses the XYZ file of a molecule to generate its 3D graphics. Some parameters can be specified by the user.
WenJun Zhang
doaj
«Life» in Tensor: Implementing Cellular Automata on Graphics Adapters
Труды Института системного программирования РАН, 2019 This paper presents an approach to the description of cellular automata using tensors. This approach allows to attract various frameworks for organizing scientific calculations on high-performance graphics adapter processors, that is, to automatically ...
Natalia Andreevna Shalyapina +1 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Design of Dot-matrix Drawing Software Used in Mine LED Electronic Display Board
Gong-kuang zidonghua, 2012 For problems of inaccurate drawing and poor visibility of mine LED electronic display board using vector technical to draw graphics, the paper proposed a design scheme of dot-matrix drawing software which can be applied in different types of electronic ...
DING Rui-qi +5 more
doaj
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source