Results 71 to 80 of about 118,973 (302)

Trend Monitoring System (TMS) graphics software

open access: yes, 1979
A prototype bus communications systems, which is being used to support the Trend Monitoring System (TMS) and to evaluate the bus concept is considered.
Brown, J. S.
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Radar amplitude-range-doppler surface fast calculation on graphics processing units

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2015
The paper describes the algorithm of fast calculation of the amplitude-range-Doppler surface. The features of the software implementation of the algorithm are drawn.
A. V. Barkhatov, A. S. Kozlov
doaj  

GENIE: a software package for gene-gene interaction analysis in genetic association studies using multiple GPU or CPU cores

open access: yesBMC Research Notes, 2011
Background Gene-gene interaction in genetic association studies is computationally intensive when a large number of SNPs are involved. Most of the latest Central Processing Units (CPUs) have multiple cores, whereas Graphics Processing Units (GPUs) also ...
Wang Kai   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A Comprehensive Survey of 3-D Graphics Software and File Formats

open access: yes, 2016
This research project is a comparative survey of various 3-D graphics software and 3-D graphics file formats, with the intention of discerning which software and file formats are superior in individual categories including, but not limited to: cost ...
Kennedy, Kendra A
core  

Developing 3D graphics software as educational material formuseum education course (The case of hunat social complex)

open access: yes, 2016
This study aims to develop a 3D graphics software that will be used during the visit of historic places in museum education course and applying this application to an example historic building.
Levent Coruh   +3 more
core   +1 more source

Supporting Sensemaking of Complex Objects with Visualizations: Visibility and Complementarity of Interactions

open access: yesInformatics, 2016
Making sense of complex objects is difficult, and typically requires the use of external representations to support cognitive demands while reasoning about the objects.
Kamran Sedig   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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