Results 71 to 80 of about 3,181,481 (300)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Software architecture visualisation [PDF]

, 2004
Tracing the history of software engineering reveals a series of abstractions. In early days, software engineers would construct software using machine code.
Hatch, Andrew
core  

Energy Demand in AR Applications—A Reverse Ablation Study of the HoloLens 2 Device

Energies
This study presents a comprehensive analysis of power consumption in the context of AR applications on the HoloLens 2. As an ablation study, the research systematically dissects various aspects, shedding light on both hardware and software components ...
Przemysław Skurowski, Dariusz Myszor, Marcin Paszkuta, Tomasz Moroń, Krzysztof A. Cyran   +4 more
doaj   +1 more source

Skeletal animation for visualizing dynamic shapes of macromolecules

Journal of Integrative Bioinformatics, 2020
We apply a skeletal animation technique developed for general computer graphics animation to display the dynamic shape of protein molecules. Polygon-based models for macromolecules such as atomic representations, surface models, and protein ribbon models
Ueno Yutaka, Muraoka Shinya, Sato Tetsuo
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Weather Graphics

, 2003
This product site for Weather Graphics Technology contains a large collection of weather-related software programs, books, videos, archived weather data, paper charts and a list of services.
Weather Graphics Technologies
core  

Constraints in object-oriented graphics [PDF]

, 1999
In the area of interactive computer graphics, two important approaches to deal with the complexity of designing and implementing graphics systems are object-oriented programming and constraint-based programming.
R. Kelleners, Kelleners, RHMC Richard, Kelleners, R. H.M. C. (Richard), Kelleners, R.H.M.C.   +3 more
core   +2 more sources

Computer graphics in Korea

, 2022
S.22-26This article presents a brief overview of the development of computer graphics research in Korea for the last 10 years. The Pacific Graphics and Korea Computer Graphics Society played an important role here they placed stepping stones for Koreans ...
Chesnais, A., Encarnação, José L.
core   +1 more source

A comparative study on teaching methods of engineering drawing course 1

آموزش مهندسی ایران, 2012
According to the modeling software and computer technology, teaching engineering graphics courses in Iranian universities must be improved similar to other top universities in the world which have changed since 2000.
Mehdi Mottaghipour
doaj   +1 more source