Results 31 to 40 of about 574,820 (303)

التعليم الإلکترونى ودوره فى فن الجرافيک بکليات الفنون الجميلة لمواکبة تکنولوجيا العصر [PDF]

open access: yesJournal of Distance Learning and Open Learning, 2014
Search provides a vision of the importance of e-learning and its objectives and its features and benefits , and their strategies as well as Arab and international experiences that have to go to be applied in different educational environments experience ...
أحمد أحمد
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Automatic Modification of Steel House Drawings by Finite Element Software for Coal Yard in Power Plant

open access: yes发电技术, 2018
In order to reduce environmental effect by open coal yard in power plant, coal yard in power plants is required to be transformed into a closed space. The closed transformation of the coal yard adopts a large steel structure.
Zhengxin LI   +3 more
doaj   +1 more source

Approximate Bayesian Image Interpretation using Generative Probabilistic Graphics Programs [PDF]

open access: yes, 2013
The idea of computer vision as the Bayesian inverse problem to computer graphics has a long history and an appealing elegance, but it has proved difficult to directly implement.
Kulkarni, Tejas D.   +3 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

CREATING AN INFORMATIONAL WEBSITE FOR PHYSICS ACADEMIC COURSE: WEB DESIGN SPECIFICS

open access: yesІнформаційні технології і засоби навчання, 2017
The article is devoted to the analysis of means and methods of creating an educational informational website for the Physics academic course. The stages of technical task creation, design of the main and typical pages of the website, layout, programming,
Іryna A. Slipukhina   +2 more
doaj  

Використання вільно поширюваних програмних засобів при вивченні комп’ютерної графіки та анімації на уроках інформатики в Технічному ліцеї [PDF]

open access: yes, 2015
The Purpose of the research is review the free software that can be used in the study of topics of computer graphics and animation on informatics lessons. The Object is a vector graphics editor Inkscape, bitmap Gimp, vector animation Synfig Studio.
Кузьменко, Алла Володимирівна
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

EVALUTION OF LEARNING FACILITIES SUPPORTING CREATIVE PRODUCTS AND ENTREPRENEURSHIP IN MODELING DESIGN AND BUILDING INFORMATION EXPERTISE COMPETENCY

open access: yesJurnal Pensil, 2023
This study aims to gain a general understanding of the state of educational infrastructure and learning facilities for creative and entrepreneurial products, as well as a general understanding of the degree of standard compliance and the appropriateness
Wisnu Rachmad Pribadi   +4 more
doaj   +1 more source

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