Results 91 to 100 of about 944,036 (244)

Synergistic grasp analysis: A cross-sectional exploration using a multi-sensory data glove

open access: yesWearable Technologies
This paper investigates hand grasping, a fundamental activity in daily living, by examining the forces and postures involved in the lift-and-hold phases of grasping.
Subhash Pratap   +2 more
doaj   +1 more source

Effects of Hand Configuration on the Grasping, Holding, and Placement of an Instrumented Object in Patients With Hemiparesis

open access: yesFrontiers in Neurology, 2019
Objective: Limitations with manual dexterity are an important problem for patients suffering from hemiparesis post stroke. Sensorimotor deficits, compensatory strategies and the use of alternative grasping configurations may influence the efficiency of ...
Ross Parry   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Algoritmo basado en metaheurística GRASP para resolver el problema de la diversidad máxima aplicado en la conformación de equipos de trabajo

open access: yesPublicaciones en Ciencias y Tecnología, 2019
En este trabajo se aborda el problema de la conformación de equipos de trabajo de la manera más diversa posible, ya que está demostrado que los equipos de trabajo diversos, funcional y demográficamente, son más eficientes para resolver problemas.
Livino Manuel Armijos Toro   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Development of a Sensor-Based System for Stroke Rehabilitation: Home-Based Dual-Task Training for the Paretic Arm

open access: yesCurrent Directions in Biomedical Engineering
Aim and focus of the research was to develop a prototype system to increase training intensity of the paretic arm and functional cognition for stroke patients through homebased rehabilitation. The key feature of this system is its ability to deliver home-
Markowski Ellen, Lehn Karsten
doaj   +1 more source

Experimental study of the discharge of granular quasi-2D silo in a uniform magnetic field [PDF]

open access: yesEPJ Web of Conferences
We present an experimental study of the discharge of a monolayer of a ferromagnetic granular medium in a quasi-2D silo surrounded by vertical uniform magnetic field.
Luce David   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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