Results 151 to 160 of about 121,712 (266)

Identification of key upper-limb muscles during a standardized reach-to-grasp task toward simplified clinical protocols. [PDF]

Front Bioeng Biotechnol
Cabezaolias C, Garcia S, Sanchez C, Rodriguez R, Raya R, Urendes E.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Quantifying Visuomotor Maturation From Middle Childhood to Adolescence. [PDF]

Dev Psychobiol
Niechwiej-Szwedo E, Christian LW.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Merging neural stimulation and exoskeletons to enhance sensorimotor hand functions after brain or spinal cord injury. [PDF]

Sci Adv
Cimolato A, Cekić D, Šećerović NK, Razzoli M, Missiroli F, Dittli J, Palopoli P, Bellomo S, Kenel J, Dujović SD, Frese S, Masia L, Djordjevic O, Lambercy O, Valle G, Konstantinovic L, Raspopovic S.   +16 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Proprioceptive judgements made with the hand and the jaw: two distinct but functionally related body parts. [PDF]

Sci Rep
Robertson LS, Butler AA, Fisher G, Gandevia SC, Héroux ME.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Use of a handheld communication tool for children and youths during dental procedures: a two-site controlled intervention study. [PDF]

Acta Odontol Scand
Rotevatn EØ, Paz ES, Løkeland LS, Guribye F, Engan GO, Gjerde CG, Lægreid T, Vatne DNB, Bergmann U, Rygh LJ, Engan M.   +10 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source