Results 21 to 30 of about 638 (208)
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
The warrior priest in Derveni grave B was a healer too
The deceased in the Derveni tombs, near Thessaloniki, Macedonia were members of an élite family of Thessalian origin, which probably lived in the nearby ancient city Lete in the 4th century BC.
Despina Ignatiadou
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Nouvelles études de tuniques romaines. Les Martres-de-Veyre (Puy-de-Dôme)
As part of the "ArchéoMartres" collective research project involving a number of Inrap staff, the re-examination of the Roman archaeological collections from the Martres-de-Veyre necropolis held by the Bargoin Museum in Clermont-Ferrand has led to the ...
Catherine Breniquet +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Stredoveký a včasnonovoveký cintorín v Nesvadoch, v polohe Jánoska part (výskum Bélu Szőkeho v rokoch 1938 a 1943). Štúdia prináša krátku informatívnu správu o cintoríne v Nesvadoch-Jánoska part. Kostolný cintorín sa nachádza na pravom brehu rieky Nitra.
Gabriel Nevizánsky, Péter Prohászka
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The article is based on the recovery and reinterpretation of archaeological data from the Nubar Hamparțumian archival fonds found at the “ Vasile Pârvan” Institute of Archaeology in Bucharest. The documents contain information about 74 burials discovered
Crețu, C., Dabîca, M., Soficaru, A.
doaj +1 more source
ABOUT THE SITE The Institute of Archaeology (Zagreb) has been excavating the stratified site of “Old Town” in the center of Ivanec, a small town in northwestern Croatia, which has yielded evidence of continuous human use from antiquity to the 20th century.
Belaj, Juraj, Sirovica, Filomena
openaire +3 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

