Results 31 to 40 of about 638 (208)

Despre cele două morminte din tell-ul de la Dridu

open access: yesMateriale și Cercetări Arheologice, 2015
Two inhumation graves (M. 1 and M. 2) were found in 1958, buried inside of a so-called tell, situated north of the medieval settlement. The two funerary structures were briefly described and published without any kind of illustration.
Oța, L., Georgescu, M., Baltă, Z.
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Burial Complex of the 1st Century AD from Kovalyovka Kurgan Gemetery

open access: yesНижневолжский археологический вестник, 2016
The present article is devoted to the burial complex of Kurgan No. 8 from Kovalyovka Cemetery located in the south of the Volga-Don interfluve, in the basin of the Aksay Yesaulovsky river. In the center of the burial mound surrounded by a circular ditch,
Aleksandr N. D’jachenko   +1 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Sarmatian children graves in Wallachia and Moldavia

open access: yesTyragetia, 2018
The studies on the social organization of the Sarmatians are still very few. The aim of this paper is to analyze children graves, in an attempt to complete, as much as possible based on the current archaeological data, the image of the Sarmatian ...
Liana Oţa
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Tumuli preistorici cercetaţi în anul 2024 în localitatea Păuleşti (jud. Prahova)

open access: yesMateriale și Cercetări Arheologice
In 2024, three prehistoric burial mounds were excavated in Păulești, uncovering four inhumation graves : three adult males and one subadult. Only the subadult grave contained grave goods — two silver hair rings.
Frînculeasa, A., Negrea, O., Ghinea, E.
doaj   +1 more source

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