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Journal of Education, Health and Sport, 2023 Background: Graves' disease is responsible for 60-80% causes of hyperthyreosis. An important role in the pathogenesis is played by anti-TSHR immunoglobulins (TRAb), that stimulate TSH receptors leading to excessive hormone synthesis and release by the ...
Natalia Woś +9 more
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Journal of Translational Autoimmunity, 2020 Genetic and family studies have indicated that Graves disease and Hashimoto thyroiditis have a heritable component which appears to be shared to some extend also with some other autoimmune diseases (AIDs).
Hauke Thomsen +5 more
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The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022 Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
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Graves-Basedow disease and potential risk factors [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow
Živanović Dušica +3 more
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Archives of Endocrinology and Metabolism, 2020 Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto +4 more
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Rituximab in the treatment of Graves’ orbitopathy: latest updates and perspectives
Endocrine Connections, 2022 Graves’ orbitopathy (GO) is a potentially sight-threatening and disfiguring, extrathyroidal manifestation of Graves’ disease. It often impairs patients’ qu ality of life, causing severe social and psychological sequelae.
Jakub Supronik +3 more
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Microchimerism in Graves’ Disease [PDF]
, 2012 Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bidirectional cell trafficking between mother and ...
Galofre, J.C. (Juan Carlos)
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In Graves' disease, increased muscle tension and reduced elasticity of affected muscles is primarily caused by active muscle contraction [PDF]
, 1989 In three patients with Graves' disease of recent onset, length-tension diagrams were made during surgery for squint under eyedrop anesthesia, while the other eye looked ahead, into the field of action, or out of the field of action of the muscle that was
Kommerell, G. (Guntram) +1 more
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A case report of immune thrombocytopenic purpura as a rare Harbinger of Graves’ disease
Journal of Clinical and Translational Endocrinology Case Reports, 2022 Graves’ disease is one of the most common forms of autoimmune hyperthyroidism and has been linked with multiple or family histories of autoimmune diseases. In most cases, Graves' disease diagnosis is easily made by recognizing goiter, ophthalmopathy, and
Handoko Hariyono, Jongky Hendro Prajitno
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Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
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