Graves’ disease with spontaneous resolution following ocrelizumab in primary progressive multiple sclerosis [PDF]
, 2021 Objectives. Immune reconstitution therapies (IRT), which include antibody-based cell-depleting therapies targeting CD52+ (alemtuzumab) or CD20+ (rituximab, ocrelizumab) leukocytes, are approved for the treatment of multiple sclerosis.
Cardoso, Helena +3 more
core +1 more source
Involvement of the Selenium Level in Plasma Glutathione Peroxidase Activity in Newly Diagnosed Patients with Graves’ Disease and Hashimoto Thyroiditis [PDF]
JOURNAL OF ADVANCES IN BIOTECHNOLOGY, 2015 Disturbed antioxidant enzymes activities was known to be associated to Auto-Immune Thyroid Diseases (AITD), but it is noteworthy that the selenoenzyme glutathione peroxidase (GPx) showed the lowest activity and a selenium (Se) deficiency may be the major cause. Most studies conducted on AITD are focused on the effect of the Se supplementation on the ...
Mohamed Abid +6 more
openaire +1 more source
BMC Endocrine Disorders, 2022 Abstract Background Graves’ disease (GD) and papillary thyroid cancer (PTC) can be concomitant. The existence of a link between these entities has long been investigated, but a clear correlation hasn’t been established. We report a case of GD resistant to medical treatment in which surgery revealed unsuspected PTC and we
Marilyn A. Arosemena +2 more
openaire +4 more sources
Isolation and characterisation of graves’ disease-specific extracellular vesicles from tissue maintained on a bespoke microfluidic device [PDF]
, 2021 This report demonstrates the ability of a microfluidic device to maintain human Graves' disease tissue enabling the isolation and characterisation of Graves' disease specific exosomes.
England, James +4 more
core +1 more source
Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease. [PDF]
Current Molecular Medicine, 2018 Thyroid-associated Ophthalmopathy (TAO) is one of the most common orbital immunological diseases in adults. CD4+ helper T (Th) cells play important roles in the pathogenesis of TAO. But the mechanisms regulating CD4+ T cell activity is unclear. This study examines T cell immunoglobulin domain and mucin domain 3 (TIM-3) expression in helper T cell type ...
Y. Liu +11 more
openaire +3 more sources
Graves\u27 Disease and Major Histocompatibility Complex Class II: A Meta-Analysis of HLA-DQ and HLA-DRB1 [PDF]
, 2023 Background: Human leukocyte antigen (HLA) class II has shown potential in determining prognosis, understanding medication reactions, and predicting onset of Graves’ disease.
Hussein, Mohamed +3 more
core +2 more sources
Microchimerism in Graves’ Disease [PDF]
, 2012 Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bidirectional cell trafficking between mother and ...
Galofre, J.C. (Juan Carlos)
core +3 more sources
Management of patients with Graves' disease and orbital involvement: role of spectral domain optical coherence tomography [PDF]
, 2018 PURPOSE: To investigate the role of choroidal thickness evaluation with spectral domain optical coherence tomography (SDOCT) and enhanced depth imaging (EDI) technique in the management of patients with Graves' disease and orbitopathy (GO).
Bruscolini, A +7 more
core +1 more source
The Pecularities of Correlation Between Insulin Resistance, Carbohydrate and Lipid Metabolism Indices in Patients with Graves'disease [PDF]
, 2017 Aim. The number of patients with endocrine disorders in the world, in particular, Graves' disease is continuously increasing. Recent studies have determined the fact of insulin resistance in thyroid disorders.
Kikhtyak, O. (Olesya) +2 more
core +2 more sources
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
core +1 more source