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Background: Graves' disease is responsible for 60-80% causes of hyperthyreosis. An important role in the pathogenesis is played by anti-TSHR immunoglobulins (TRAb), that stimulate TSH receptors leading to excessive hormone synthesis and release by the ...
Natalia Woś+9 more
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Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
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Involvement of the Selenium Level in Plasma Glutathione Peroxidase Activity in Newly Diagnosed Patients with Graves’ Disease and Hashimoto Thyroiditis [PDF]
Disturbed antioxidant enzymes activities was known to be associated to Auto-Immune Thyroid Diseases (AITD), but it is noteworthy that the selenoenzyme glutathione peroxidase (GPx) showed the lowest activity and a selenium (Se) deficiency may be the major cause. Most studies conducted on AITD are focused on the effect of the Se supplementation on the ...
Mohamed Abid+6 more
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Abstract Background Graves’ disease (GD) and papillary thyroid cancer (PTC) can be concomitant. The existence of a link between these entities has long been investigated, but a clear correlation hasn’t been established. We report a case of GD resistant to medical treatment in which surgery revealed unsuspected PTC and we
Marilyn A. Arosemena+2 more
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Graves-Basedow disease and potential risk factors [PDF]
Background/Aim. Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow
Živanović Dušica+3 more
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Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto+4 more
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Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease. [PDF]
Thyroid-associated Ophthalmopathy (TAO) is one of the most common orbital immunological diseases in adults. CD4+ helper T (Th) cells play important roles in the pathogenesis of TAO. But the mechanisms regulating CD4+ T cell activity is unclear. This study examines T cell immunoglobulin domain and mucin domain 3 (TIM-3) expression in helper T cell type ...
Y. Liu+11 more
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Rituximab in the treatment of Graves’ orbitopathy: latest updates and perspectives
Graves’ orbitopathy (GO) is a potentially sight-threatening and disfiguring, extrathyroidal manifestation of Graves’ disease. It often impairs patients’ qu ality of life, causing severe social and psychological sequelae.
Jakub Supronik+3 more
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Radioiodine treatment for graves’ disease: a 10-year Australian cohort study
Background Radioactive iodine (I131) is a common definitive treatment for Graves’ Disease. Potential complications include worsening, or new development of Graves’ eye disease and development of a radiation thyroiditis.
Erin Fanning+2 more
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Riedel Thyroiditis in a Patient with Graves Disease [PDF]
Riedel's thyroiditis is a rare form of infiltrative and inflammatory disease of the thyroid gland and can be associated with systemic fibrotic processes, Hashimoto thyroiditis and Graves disease.
Doo Young Lee+4 more
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