Results 31 to 40 of about 5,085,125 (242)

Candidate gene associations reveal sex‐specific Graves’ disease risk alleles among Chinese Han populations

Molecular Genetics & Genomic Medicine, 2020
Background With several susceptibility single nucleotide polymorphisms identified by case–control association studies, Graves’ disease is one of the most common forms of autoimmune thyroid disease.
Chen‐Yan Yan, Yu‐Ru Ma, Feng Sun, Rui‐Jia Zhang, Ya Fang, Qian‐Yue Zhang, Feng‐Yao Wu, Shuang‐Xia Zhao, Huai‐Dong Song   +8 more
doaj   +1 more source

Additional file 1: of Progressive stenosis and radiological findings of vasculitis over the entire internal carotid artery in moyamoya vasculopathy associated with gravesâ disease: a case report and review of the literature

, 2019
Figure S1. MR imaging of cerebral infarction in the first episode. Axial diffusion-weighted images showed infarcts in the left cerebral hemisphere. (PDF 202 kb)
Ito, Hiroto, Yokoi, Syunsuke, Yokoyama, Kinya, Asai, Takumi, Uda, Kenji, Araki, Yoshio, Takasu, Syuntaro, Kobayashi, Rei, Okada, Hisashi, Okuda, Satoshi   +9 more
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Steroid Treatment Focused Management of Graves’ Ophthalmopathy

Acta Medica Bulgarica
Graves' disease (GD) is an autoimmune disease that affects the thyroid and the eyes. Graves' ophthalmopathy (GO), an autoimmune disease, usually appears 18 months after GD diagnosis.
Condeng Y. H., Umar H., Aman A. M., Rasyid H., Bakri S., Iskandar H.   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Aneurysmal bone cyst of the proximal femur concomitant with Graves’ disease and Moyamoya disease: report of a rare case

Journal of International Medical Research, 2022
Aneurysmal bone cyst is a type of benign bone pathology with expansile and osteolytic features whose etiology remains unclear. Graves’ disease is an autoimmune disease characterized by diffuse goiter and hyperthyroidism. Moyamoya disease is a progressive
Cai Gao-Rui, Chen Guo-Neng, Jiang Wen-Xue   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Dermopathy of Graves′ disease: Clinico-pathological correlation

Indian Journal of Endocrinology and Metabolism, 2012
Dermopathy of Graves′ disease is a classical, but uncommon extrathyroidal manifestation of Graves′ disease. The images of a typical case of dermopathy of Graves′ disease are presented along with clinico-pathological correlation.
Sagili Vijaya Bhaskar Reddy, Sushil Kumar Gupta, Manoj Jain   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source