Results 51 to 60 of about 5,085,125 (242)

Association between thymic hyperplasia and serum calcium level in Graves’ disease

open access: yesBMC Endocrine Disorders
Background Graves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic hyperplasia is observed in some Graves' disease patients.
Jing Zeng, Lan Li, Dong Wei
doaj   +1 more source

Clinical and immunological aspects of cardiovascular disorders in Graves' disease and chronic heart failure

open access: yesКлиническая и экспериментальная тиреоидология, 2011
The aim of the study was to estimate a level of thyrotropin-receptor antibodies (TRAb), some cytokines (TNF-α, IL-8, IL-10) in Graves' disease patients with chronic heart failure (CHF) and to reveal prognostic factors of CHF.89 patients with Graves ...

doaj   +1 more source

Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden

open access: yesJournal of Translational Autoimmunity, 2020
Genetic and family studies have indicated that Graves disease and Hashimoto thyroiditis have a heritable component which appears to be shared to some extend also with some other autoimmune diseases (AIDs).
Hauke Thomsen   +5 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Graves’ Disease and Diagnostic Approaches

open access: yesEndocrinology Research and Practice, 2007
Although thyroid stimulating hormone receptor antibody (TSH-Rab) is pathogonomonic for Graves’ disease, antibodies against thyroglobulin, thyroperoxidase can also be detected in serum of patients. Many authors propose that ophtalmopathy and/or dermopathy
Melek Eda Ertörer   +4 more
doaj   +2 more sources

Effects of Radioiodine Therapy on the Natural History of Graves' Ophtalmopathy

open access: yesКлиническая и экспериментальная тиреоидология, 2007
21 patients with Graves’ disease and Graves’ ophthalmopathy (GO) received radioiodine treatment (RIT). Before 131-I therapy in all patients GO were non-active and no severe.

doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Thyrotropin Receptor Antibody Levels in Patients with Autoimmune Thyroid Disease in Iodine Deficient Areas

open access: yesEndocrinology Research and Practice, 2022
In this study, we investigated Thyrotropin Receptor Antibody (TRab) levels in Hashimoto and Graves' diseases. A total of 189 patients and 25 controls were assessed, retrospectively.
Demet Çorapçıoğlu   +8 more
doaj   +2 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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