Results 61 to 70 of about 64,440 (255)

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Mouse Model of Graves’ Orbitopathy in Current Research and Future Perspectives

Medicina
Graves’ orbitopathy (GO) is a representative extrathyroidal manifestation of autoimmune thyroid disease. Despite extensive research, the precise pathogenic mechanisms remain incompletely understood. Moreover, the lack of an ideal animal model has limited
Gyeong Min Lee, Wook Hyun Jung, Yeseul Kim, Myung In Oh, Sun Young Jang   +4 more
doaj   +1 more source

Thyrotropin receptor antibodies measured by second-generation assay are highly specific for Graves’ disease and correlate with serum thyrotropin levels in patients with Graves’ disease inremission and during maintenance therapy [PDF]

, 2008
We compared conventional first-generation thyrotropin receptor antibodies（F-TRAb）and second-generation TRAb （S-TRAb, DYNOtest） in sera. Subjects were 167 cases of Graves’ disease, 5 cases of painless thyroiditis, 8 cases of subacute thyroiditis, 37 cases
Kusaka, Ikuyo, Muroi, Rika, Kawakami, Akio, Nagasaka, Shoichiro, Ishibashi, Shun, Rokkaku, Kumiko   +5 more
core  

Overweight as a biomarker for concomitant thyroid cancer in patients with Graves’ disease

Frontiers in Endocrinology
The incidence of concomitant thyroid cancer in Graves’ disease varies and Graves’ disease can make the diagnosis and management of thyroid nodules more challenging. Since the majority of Graves’ disease patients primarily received non-surgical treatment,
Joonseon Park, Solji An, Ja Seong Bae, Jeong Soo Kim, Kwangsoon Kim   +4 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source

Current concepts in Graves’ disease

, 2011
Graves’ disease is the most common cause of hyperthyroidism in the developed world. It is caused by an immune defect in genetically susceptible individuals in whom the production of unique antibodies results in thyroid hormone excess and glandular ...
Christian M. Girgis, Bernard L. Champion, Jack R. Wall   +2 more
core   +1 more source

Discordance Between Systemic Lupus Erythematosus Disease Activity Index Domain Weights and Their Association With Organ Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

Thymic hyperplasia in Graves′ disease

, 2013
Graves′ disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. It is known to be associated with autoimmune conditions such as myasthenia gravis, Addison′s disease, type 1 diabetes ...
Anil Menon, Yashpal Singh, Vineet Behera, Narendra Kotwal   +3 more
core   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

A randomized controlled trial on the effect of hydroxychloroquine in mild Graves’ orbitopathy (GO-HCQ): study protocol

Trials
Background Graves’ orbitopathy (GO) is a prevalent manifestation of Graves’ disease (GD), characterized by proptosis, eyelid retraction, soft tissue swelling, diplopia, and potential visual acuity impairment.
Chia-Hung Lin, Yi-Hsuan Wei, Jin-Ying Lu, Hung-Yuan Li, Chung-Wei Lee, Chung-Yi Yang, Chin-Hao Chang, Wan-Chen Wu, Chih-Yuan Wang, Shyang-Rong Shih   +9 more
doaj   +1 more source