Results 31 to 40 of about 53,663 (280)

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

A Literature Review of Concomitant Primary Biliary Cirrhosis and GravesÂ’ Disease

Journal of Gastrointestinal & Digestive System, 2015
Although Hashimoto’s thyroiditis (HT) is commonly characterized by extrahepatic manifestations of primary biliary cirrhosis (PBC), coexistence of PBC and Graves’ disease (GD) is uncommon. This is a review of the English and Japanese scientific literature, comprising 7 cases of PBC and GD coexistence. All patients were female.
openaire   +2 more sources

Additional file 1: of Progressive stenosis and radiological findings of vasculitis over the entire internal carotid artery in moyamoya vasculopathy associated with gravesâ disease: a case report and review of the literature

, 2019
Figure S1. MR imaging of cerebral infarction in the first episode. Axial diffusion-weighted images showed infarcts in the left cerebral hemisphere. (PDF 202 kb)
Ito, Hiroto, Syunsuke Yokoi, Yokoyama, Kinya, Asai, Takumi, Uda, Kenji, Araki, Yoshio, Syuntaro Takasu, Kobayashi, Rei, Okada, Hisashi, Okuda, Satoshi   +9 more
openaire   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

A Case of Graves’ Disease Accompanied with Acute Hepatitis A Virus Infection

The Korean Journal of Gastroenterology, 2018
Concurrent presentation of acute hepatitis A virus (HAV) infection and Graves’ disease has not been reported in literature worldwide. Although there is no well-established mechanism that explains the induction of Graves’ disease by HAV to date, our case ...
Seong Eun Hong, Jin Woo Choo, Soo Kyung Lim, Seong Jin Lee, Ji Won Park, Sung Eun Kim, Jong Hyeok Kim, Choong Kee Park   +7 more
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A case report of immune thrombocytopenic purpura as a rare Harbinger of Graves’ disease

Journal of Clinical and Translational Endocrinology Case Reports, 2022
Graves’ disease is one of the most common forms of autoimmune hyperthyroidism and has been linked with multiple or family histories of autoimmune diseases. In most cases, Graves' disease diagnosis is easily made by recognizing goiter, ophthalmopathy, and
Handoko Hariyono, Jongky Hendro Prajitno
doaj  

Acute Pericarditis as an Uncommon Presentation of Graves’ Disease

Oman Medical Journal, 2022
Cardiovascular manifestations are well recognized features of hyperthyroidism, particularly Graves’ disease. Common cardiac complications include atrial fibrillation, hypertension, and high or normal output congestive heart failure.
Abdullah Al-Futaisi, Moammar Al-Aamri, Fatima Bahowairath, Mahmood Saif Al Jufaili   +3 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source