Results 81 to 90 of about 278,227 (245)

Comparative analysis of dosimetric parameters of three different radiation techniques for patients with Graves' ophthalmopathy treated with retro-orbital irradiation [PDF]

, 2012
published_or_final_versio
Au, GKH, Choi, CW, Kwong, DLW, Lee, VHF, Leung, TW, Luk, MY, Ng, CY   +6 more
core   +1 more source

The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta‐analysis of randomised controlled trials

Clinical Endocrinology
Selenium is a trace element crucial for thyroid function, and has potential therapeutic benefits in Graves' orbitopathy (GO). Therefore, we aim to evaluate its efficacy and safety in GO patients to provide valuable insights into its role as a therapeutic
Israa Sharabati, R. Qafesha, M. Hindawi, S. Amro, Baraa M Ayesh   +4 more
semanticscholar   +1 more source

A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves’ orbitopathy

Cellular & Molecular Immunology, 2021
Graves’ orbitopathy (GO), the most severe manifestation of Graves’ hyperthyroidism (GH), is an autoimmune-mediated inflammatory disorder, and treatments often exhibit a low efficacy.
Yue Wang, Ziyi Chen, Tingjie Wang, Hui Guo, Yufeng Liu, Ningxin Dang, Shiqian Hu, Li-ping Wu, Chengsheng Zhang, K. Ye, B. Shi   +10 more
semanticscholar   +1 more source

Application of Machine Learning to Discriminate Photoreceptor Cell Species in Xenotransplanted Chimeric Retinas

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Photoreceptor transplantation is being studied to restore visual function in retinal diseases causing blindness, including age‐related macular degeneration, hereditary eye diseases, and traumatic retinopathy. Preclinical studies often involve delivering exogenous human photoreceptor cells into animal models' retinas.
Kang V. Li, Annabelle Pan, Ying V. Liu, Bani Antonio‐Aguirre, Joyce Wang, McKaily Adams, Christina McNerney, Sai Bo Bo Tun, Kenneth Jimenez, Yuchen Lu, Zhuolin Li, Minda McNally, Veluchamy A. Barathi, Robert J. Johnston Jr., Mandeep S. Singh   +14 more
wiley   +1 more source

Neural Network-Based Pipeline With High-Resolution Feature Enhancement and Low-Resolution Feature Preservation for Automated Treatment Decision of Graves’ Orbitopathy Patients

IEEE Access
Graves’ orbitopathy is an inflammatory disorder that causes changes in different structures close to the eye. Accurate and consistent diagnoses are essential to improve the quality of life for Graves’ orbitopathy patients.
Sanghyuck Lee, Mohd Asyraf Zulkifley, Jeong Kyu Lee, Jaesung Lee   +3 more
doaj   +1 more source

The Role of the Microbiota in Graves’ Disease and Graves’ Orbitopathy

Frontiers in Cellular and Infection Microbiology, 2021
Graves‘ disease (GD) is a clinical syndrome with an enlarged and overactive thyroid gland, an accelerated heart rate, Graves’ orbitopathy (GO), and pretibial myxedema (PTM). GO is the most common extrathyroidal complication of GD. GD/GO has a significant
Jueyu Hou, Yunjing Tang, Yongjiang Chen, Danian Chen   +3 more
semanticscholar   +1 more source

Glymphatic System Dysfunction in Thyroid‐Associated Ophthalmopathy: A Multimodal MRI Study

CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
TAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Lijie Zhang, Jiaqi Yao, Yiming Qi, Yongheng Luo, Jun Liu   +4 more
wiley   +1 more source

Graves’ orbitopathy: lessons from Representational Art

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2021
Graves’ orbitopathy (GO) is an autoimmune orbital disorder which occurs most commonly in patients with Graves’ disease,  less frequently in patients with chronic autoimmune thyroiditis.
Francesco Trimarchi, Enio Martino, Maria Laura Tanda, Luigi Bartalena   +3 more
doaj   +1 more source

Mesenchymal Stem Cell–Like Properties of Orbital Fibroblasts in Graves’ Orbitopathy [PDF]

, 2015
PURPOSE. Graves’ orbitopathy (GO) is a sight-threatening autoimmune disorder causing extraocular muscle fibrosis, upper lid retraction and eye bulging due to orbital fat expansion.
Bailly, M, Ezra, DG, Fitchett, C, Kozdon, K, Rose, GE   +4 more
core   +1 more source

Rapamycin improves Graves’ orbitopathy by suppressing CD4+ cytotoxic T lymphocytes

JCI Insight, 2022
CD4+ cytotoxic T lymphocytes (CTLs) were recently implicated in immune-mediated inflammation and fibrosis progression of Graves’ orbitopathy (GO). However, little is known about therapeutic targeting of CD4+ CTLs.
Meng Zhang, K. Chong, Ziyi Chen, Hui Guo, Yu-feng Liu, Yongyong Kang, Yang Li, T. Shi, K. Lai, Mingqian He, Kai Ye, G. Kahaly, B. Shi, Yue Wang   +13 more
semanticscholar   +1 more source