Results 61 to 70 of about 224,676 (168)
Hyera Kang,1,2 Yasuhiro Takahashi,1 Masayoshi Iwaki,1 Shinichi Asamura,3 Hirohiko Kakizaki,11Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Department of Ophthalmology, Presbyterian Medical Center, Jeonju, Korea ...
Kang H +4 more
doaj
Alemtuzumab-induced thyroid eye disease successfully treated with a single low dose of rituximab
Introduction: Secondary thyroid autoimmunity, especially Graves’ disease (GD), frequently develops in patients with multiple sclerosis (MS) following alemtuzumab treatment (ALTZ; anti-CD52). Thyroid eye disease (TED) can also develop, and rituximab (RTX;
Ilaria Muller +10 more
doaj +1 more source
Mechanistic Pathways of Selenium in the Treatment of Graves' Disease and Graves' Orbitopathy
Based on the role of oxidative stress in the pathogenesis of Graves' hyperthyroidism and Graves' orbitopathy, the use of the antioxidant agent selenium has been proposed and several studies on the subject have been conducted, both in vitro and in vivo ...
Leo, Marenza +3 more
core +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
RNFL Study in Graves Orbitopathy
Purpose:to determine changes of retinal nerve fiber layer (RNFL) in a group of patients with serious thyroid-related immune orbitopathy and compare it with a group of patients with moderate Graves orbitopathy.
CAMPANERUT, SARA +4 more
core
Purpose Thyroid eye disease (TED) is the most common orbital disorder in adults. Its initial clinical manifestations are heterogeneous and may influence early diagnosis and management. However, limited data exist on real‐world perspectives from oculoplastic surgeons who frequently manage patients with TED.
Shiqi Hui +4 more
wiley +1 more source
Alemtuzumab‐Induced Graves’ Disease Complicated by Pretibial Myxoedema: A Case Report
Background Alemtuzumab, a monoclonal antibody targeting CD52, is associated with a high incidence of secondary autoimmune disease, most commonly thyroid dysfunction. Alemtuzumab‐induced Graves’ disease (AIGD) typically follows a relapsing course and may exhibit atypical or severe phenotypes during immune reconstitution (IR). Case Presentation We report
Aongus O’Brolchain +2 more
wiley +1 more source
Graves′ orbitopathy: Management of difficult cases
Management of Graves′ ophthalmopathy (GO) is based on three pillars: to stop smoking, to restore and maintain euthyroidism, and to treat the eye changes according to severity and activity of GO.
Wilmar M Wiersinga
doaj +1 more source
EMERGENCY TREATMENT OF GRAVES ORBITOPATHY
GRAVES ORBITOPATHY EMERGENCY DEPARTMENT SUDDEN IMPAIRMENT ...
CARINI, Luisa +8 more
core

