Results 41 to 50 of about 7,608 (177)

Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]

, 2017
BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Antonelli, A, Couch, SM, Dailey, RA, Douglas, RS, Ezra, DG, Fleming, JC, Gabriel, K, Gigantelli, JW, Goldberg, RA, Harris, GJ, Hayek, BR, Hink, EM, Kahaly, GJ, Magni, G, Salvi, M, Shriver, EM, Smith, TJ, Tang, RA, Woodward, RM   +18 more
core   +1 more source

From Immunization to Autoimmunity: A Deep Dive Into Post‐COVID‐19 Vaccine Reactions—A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Coronavirus disease‐2019 (COVID‐19) emerged in 2019 from Wuhan, China, leading to the accelerated development of vaccines, which have proven instrumental in controlling the spread of the virus. While vaccination ceased the increasing trend of the viral infection, rare adverse autoimmune events emerged as important ...
Mohammad Javad Yousefi‐Hashemabad, Saeed Hashemi, Kiarash Saleki, Seyed Mohamad Kazem Nourbakhsh, Andia Saleki, Zahra Hassanzadeh, Abbas Azadmehr   +6 more
wiley   +1 more source

Significance of HLA in Graves’ disease and Graves’ orbitopathy in Asian and Caucasian populations – a systematic review

Frontiers in Immunology, 2023
IntroductionGraves’ disease (GD) and Graves’ orbitopathy (GO) development were suspected to be HLA-related in both Asian and Caucasian populations. However, most studies were performed with application of serological methods or low resolution genetic ...
Magdalena Stasiak, Bartłomiej Stasiak, Katarzyna Zawadzka-Starczewska, Andrzej Lewiński, Andrzej Lewiński   +4 more
doaj   +1 more source

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei, Béla Kajtár, Tamás László, Hazem A Juratli, Livia Vida, Ágota Szepesi, Réka Mózes, Botond Timár, Jörg Halter, Stefan Dirnhofer, Alexandar Tzankov   +10 more
wiley   +1 more source

Successful outcome of Rituximab treatment based on lymphocyte immunophenotyping in active Thyroid Eye Disease: a case report

Thyroid Research
Background Rituximab, an anti-CD20 monoclonal antibody that depletes B-cells, is a potential second-line treatment for moderate-to-severe active Thyroid Eye Disease that is resistant to steroids.
Mirco Armenti, Sara Maioli, Chiara Riva, Nicola Currò, Giorgia Moschetti, Mario Salvi, Ilaria Muller   +6 more
doaj   +1 more source

Diagnostic accuracy of short-time inversion recovery sequence in Graves' ophthalmopathy before and after prednisone treatment [PDF]

, 2014
Introduction: In Graves' Ophthalmopathy, it is important to distinguish active inflammatory phase, responsive to immunosuppressive treatment, from fibrotic unresponsive inactive one.
Belfiore, M. P., Cappabianca, S., Carella, C., Cirillo, M., Cirillo, S., ELEFANTE, ANDREA, Prudente, M., Romano, F., Tortora, F.   +8 more
core   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

Bioelectronic Technology for Nutritional Research—a Novel In Vitro Platform for a Better Understanding of Human Gut Barrier Absorption

Advanced Biology, Volume 10, Issue 2, February 2026.
This is the first study to demonstrate that the e‐transmembrane gut model provides more accurate physiological predictions than conventional cell culture inserts when tested by the dietary compound butyrate. The bioelectronic e‐transmembrane platform integrates technological and biological optimizations, enabling the hosting of a complex human gut in ...
Verena Stoeger, Magdalena Strauss, Kumar Thurimella, Shani Elias‐Kirma, Izabella Niewczas, Etkin Parlar, Erika Schaudy, Chrysanthi‐Maria Moysidou, Stephen Voong, Jory Lietard, Jonathan Clark, Christopher Gerner, Róisín M. Owens   +12 more
wiley   +1 more source

Effectiveness of Selenium Supplementation in the Treatment of Graves–Basedow Disease: A Scoping Review

Medical Sciences
Background: Graves–Basedow disease (GBD) is an autoimmune thyroid disorder characterized by loss of tolerance to the thyrotropin receptor, with clinical manifestations such as a hyperadrenergic state, goiter, orbitopathy, and myxedema, inter alia ...
Hernando Vargas-Uricoechea, Alejandro Castellanos-Pinedo, Karen Urrego-Noguera, María V. Pinzón-Fernández, Ivonne A. Meza-Cabrera, Hernando Vargas-Sierra   +5 more
doaj   +1 more source

Graves’ disease and exophthalmos — a mask for meningioma

Endokrynologia Polska, 2021
Not required for Clinical Vignette.
Kamila Mitka, Grzegorz Sokołowski, Dorota Pach, Alicja Hubalewska-Dydejczyk   +3 more
doaj   +1 more source