Results 41 to 50 of about 230,556 (169)

Factors affecting the course of Graves' Orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy [PDF]

, 2022
Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity.
Sokołowski, Andrzej, Jagiełło-Korzeniowska, Agnieszka, Romanowska-Dixon, Bożena, Hubalewska-Dydejczyk, Alicja, Bałdys-Waligórska, Agata, Agata Bałdys-Waligórska, Alicja Hubalewska-Dydejczyk, Bożena Romanowska-Dixon, Agnieszka Jagiełło-Korzeniowska, Andrzej Sokołowski   +9 more
core   +2 more sources

Diagnostic Options in Graves' or Non‐Graves' Thyrotoxicosis: A Review for Clinical Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Distinguishing Graves' disease (GD) from the other causes of thyrotoxicosis is essential for appropriate management. The clinical phenotype of GD has evolved over time and is currently more heterogenous and milder than in the past. Consequently, the differential diagnosis of thyrotoxicosis is often challenging.
Lorenzo Scappaticcio, Pierpaolo Trimboli, Paola Caruso, Chiara Porcellini, Daniela Forestiere, Maria Ida Maiorino, Katherine Esposito, Giuseppe Bellastella   +7 more
wiley   +1 more source

Graves' orbitopathy treated with immunosuppressive therapy and orbital radiotherapy in a tertiary care endocrine centre: case series

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016
Graves’ Orbitopathy (GO) is a localized entity of Graves’ disease, which is a challenging disease to treat. We describe 6 cases of moderate to severe GO who presented to our endocrine centre, with a mean age of 48.6 years and equal gender distribution ...
D. C. Kottahachchi, W. K. M. G. Amarawardena, N. A. S. Ariyawansa, S. Siyambalapitiya, K. A. Perera   +4 more
doaj   +1 more source

The Tutopatch® assisted surgery for complex strabismus study: TASCS‐study

Acta Ophthalmologica, Volume 104, Issue 7, Page 818-827, November 2026.
Abstract Purpose To investigate the efficacy of tendon elongation using bovine pericardium (Tutopatch®) in complex strabismus surgeries, with a specific focus on longer follow‐up of postoperative outcomes and patient satisfaction. Methods In this pre‐post cohort study, the records of all patients who underwent tendon elongation strabismus surgery with ...
Ires A. W. Verhees, Hinke Marijke Jellema, Anne‐Marie E. L. Langenhorst, B. Jeroen Klevering, Laurentius J. van Rijn, Annabel L. W. Groot   +5 more
wiley   +1 more source

Successful outcome of Rituximab treatment based on lymphocyte immunophenotyping in active Thyroid Eye Disease: a case report

Thyroid Research
Background Rituximab, an anti-CD20 monoclonal antibody that depletes B-cells, is a potential second-line treatment for moderate-to-severe active Thyroid Eye Disease that is resistant to steroids.
Mirco Armenti, Sara Maioli, Chiara Riva, Nicola Currò, Giorgia Moschetti, Mario Salvi, Ilaria Muller   +6 more
doaj   +1 more source

Impact of Steroid Pulse Therapy on Early Treatment Response and Relapse in Type 1 Autoimmune Pancreatitis

JGH Open, Volume 10, Issue 7, July 2026.
ABSTRACT Aims Despite the recommendation of steroid therapy for type 1 autoimmune pancreatitis (AIP), the value of steroid pulse therapy remains unclear. This study aimed to assess the efficacy and safety of steroid pulse therapy in patients with AIP. Methods and Results Of 121 patients with type 1 AIP who were identified, 116 with adequate follow‐up ...
Akihisa Adachi, Itaru Naitoh, Michihiro Yoshida, Yasuki Hori, Akihisa Kato, Kenta Kachi, Tadashi Toyohara, Kayoko Oda, Yusuke Kito, Kenji Urakabe, Toshitaka Mori, Hiromi Kataoka   +11 more
wiley   +1 more source

Genetic profiling of orbital fibroblasts from patients with Graves' orbitopathy

, 2021
Graves' orbitopathy (GO) is an autoimmune disease persisting when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms ...
Dottore, Giovanna Rotondo, Lanzolla, Giulia, Casini, Giamberto, Dallan, Iacopo, Rotondo Dottore, Giovanna, Torregrossa, Liborio, Basolo, Fulvio, Marcocci, Claudio, Bucci, Ilaria, Nardi, Marco, Marinò, Michele, Sframeli, Angela, Figus, Michele, Nardi M., Rotondo Dottore G., Sframeli A., Casini G., Dallan I., Marino M., Bucci I., Figus M., Torregrossa L., Basolo F., Lanzolla G., Marcocci C., Liborio Torregrossa, Iacopo Dallan, Giulia Lanzolla, Angela Sframeli, Claudio Marcocci, Giamberto Casini, Giovanna Rotondo Dottore, Fulvio Basolo, Marco Nardi, Ilaria Bucci, Michele Marinò, Michele Figus   +36 more
core   +1 more source

The Value of Multidetector Computed Tomography of Orbits in Globe Protrusion in Comparison to Hertel Exophthalmometry

Acta Clinica Croatica, 2017
The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. Th e aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel ...
Igor Đorić, Miloš Žarković, Zoran Radojičić, Nikola Repac, Aleksandar Janićijević, Krešimir Rotim, Goran Tasić, Lukas Rasulić   +7 more
doaj   +1 more source

Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves' orbitopathy [PDF]

, 2012
BACKGROUND: Optimal doses of i.v. glucocorticoids for Graves' orbitopathy (GO) are undefined. METHODS: We carried out a multicenter, randomized, double-blind trial to determine efficacy and safety of three doses of i.v. methylprednisolone in 159 patients
Bernard M, for the European Group on Graves' Orbitopathy, Soeters, M R, Currò N, Nardi, M, Mourits, M P, Salvi M, Boboridis KG, Stahl, M, Daumerie C, Azzolini, C, Sassi, L, Boschi A, MARCOCCI, CLAUDIO, Currò, N, Wiersinga W, von Arx, G, Bournaud C, Boboridis, K G, Stahl M, Bartalena L, BALDESCHI, LELIO, Veronesi, G, Baldeschi, L, Krassas GE, Krassas G, Baldeschi L, Veronesi G, Boschi, Antonella, VERONESI, GIOVANNI, Marcocci, C, SASSI, LORENZA, Azzolini C, Mourits MP, Nardi M, Wiersinga, W, AZZOLINI, CLAUDIO, NARDI, MARCO, Bernard, M, for the European Group on Graves Orbitopathy, von Arx G, European Group on Graves' Orbitopathy, Marcocci C, Daumerie, Chantal, Wiersinga WM, BARTALENA, LUIGI, Bournaud, C, Salvi, M, Soeters MR, Sassi L, Curr? N, Krassas, G E, Bartalena, L   +52 more
core   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source