Results 41 to 50 of about 4,399 (136)
Test–retest reliability of clinical accommodative measures in adolescents
ABSTRACT Purpose To determine long‐term (3 months) test–retest reliability of accommodative testing in adolescents with normal accommodative amplitude. Methods Participants aged 12 years to <17.5 years with normal accommodative amplitude (minimum of 11 diopters [D]) and binocular vision were enrolled.
Angela M. Chen +11 more
wiley +1 more source
Background Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be life-threatening. The objective of
Dorota Walasik-Szemplińska +2 more
doaj +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
Thyroid associated orbitopathy
Thyroid associated orbitopathy, also known as Graves′ orbitopathy, is typically a self-limiting autoimmune process associated with dysthyroid states.
Rajat Maheshwari, Ezekiel Weis
doaj +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
Clinical assessment of patients with Graves' orbitopathy [PDF]
Clinical examination is the basis of a good assessment of a patient with Graves' orbitopathy. This study gives recommendations of the European orbitopathy group related to the activity and severity of the disease. The activity of the disease is estimated
Nedeljković-Beleslin Biljana
doaj +1 more source
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
Hyera Kang,1,2 Yasuhiro Takahashi,1 Masayoshi Iwaki,1 Shinichi Asamura,3 Hirohiko Kakizaki,11Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Department of Ophthalmology, Presbyterian Medical Center, Jeonju, Korea ...
Kang H +4 more
doaj
Alemtuzumab-induced thyroid eye disease successfully treated with a single low dose of rituximab
Introduction: Secondary thyroid autoimmunity, especially Graves’ disease (GD), frequently develops in patients with multiple sclerosis (MS) following alemtuzumab treatment (ALTZ; anti-CD52). Thyroid eye disease (TED) can also develop, and rituximab (RTX;
Ilaria Muller +10 more
doaj +1 more source
Purpose Thyroid eye disease (TED) is the most common orbital disorder in adults. Its initial clinical manifestations are heterogeneous and may influence early diagnosis and management. However, limited data exist on real‐world perspectives from oculoplastic surgeons who frequently manage patients with TED.
Shiqi Hui +4 more
wiley +1 more source

