Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves' orbitopathy [PDF]
BACKGROUND: Optimal doses of i.v. glucocorticoids for Graves' orbitopathy (GO) are undefined. METHODS: We carried out a multicenter, randomized, double-blind trial to determine efficacy and safety of three doses of i.v. methylprednisolone in 159 patients
Bernard M +72 more
core +1 more source
Late recurrence of unilateral graves orbitopathy on the contralateral side
PURPOSE: To report a case of late recurrence of unilateral Graves orbitopathy on the contralateral side after 7 years. DESIGN: Interventional case report.
Mourits, Maarten P. +3 more
core +2 more sources
What has changed in thyroid eye disease in the last five years (2020–2025)
Background: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj +1 more source
Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy
Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei +4 more
doaj +1 more source
Antioxidant Therapy in Graves’ Orbitopathy
The balance of the cell redox state is a key point for the maintenance of cellular homeostasis. Increased reactive oxygen species (ROS) generation leads to oxidative damage of tissues, which is involved in the development of several diseases, including ...
Giulia Lanzolla +2 more
doaj +1 more source
ObjectiveManagement of Graves’ orbitopathy remains a challenge. Our previous case report has shown promising results for rabbit antithymocyte globulin (rATG) in the treatment of Graves’ orbitopathy.DesignWe present the response of 7 individuals with ...
Monika Sarnat-Kucharczyk +8 more
doaj +1 more source
We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu +3 more
doaj +1 more source
Orbital lymphoma associated with Graves’ disease: A case report [PDF]
Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran +4 more
doaj +1 more source
Aggravated Orbitopathy Following Remnant Ablation in a Patient with Multiple Cancers
The rate of thyroid cancer in the patients with Graves’ disease is controversial. The rare incidents of multiple primary thyroid cancers in the same patient have been reported.
Umut MOUSA +4 more
doaj +1 more source
Muscle tendon elongation with bovine pericardium (Tutopatch®) in patients with Graves' orbitopathy; a prospective, observational, multicentre study. [PDF]
Abstract Purpose Patients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative.
Jellema HM +7 more
europepmc +2 more sources

