Results 31 to 40 of about 230,556 (169)

What has changed in thyroid eye disease in the last five years (2020–2025)

European Thyroid Journal
Background: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj   +1 more source

Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy

BMC Ophthalmology, 2018
Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei, Zita Steiber, Csaba Molnar, Ervin Berenyi, Endre V. Nagy   +4 more
doaj   +1 more source

Antioxidant Therapy in Graves’ Orbitopathy

Frontiers in Endocrinology, 2020
The balance of the cell redox state is a key point for the maintenance of cellular homeostasis. Increased reactive oxygen species (ROS) generation leads to oxidative damage of tissues, which is involved in the development of several diseases, including ...
Giulia Lanzolla, Claudio Marcocci, Michele Marinò   +2 more
doaj   +1 more source

Antithymocyte Globulin as Second-Line Therapy in Graves Orbitopathy—Preliminary Results From a Prospective Single-Center Study

Frontiers in Endocrinology, 2022
ObjectiveManagement of Graves’ orbitopathy remains a challenge. Our previous case report has shown promising results for rabbit antithymocyte globulin (rATG) in the treatment of Graves’ orbitopathy.DesignWe present the response of 7 individuals with ...
Monika Sarnat-Kucharczyk, Maria Świerkot, Gabriela Handzlik, Grażyna Kulawik, Krystyna Jagoda, Iga Grochoła-Małecka, Joanna Fryżewska, Ewa Mrukwa-Kominek, Jerzy Chudek   +8 more
doaj   +1 more source

Thyroid Eye Disease due to Immune Reconstitution Inflammatory Syndrome as a Consequence of Antiretroviral Therapy in the Setting of AIDS

Case Reports in Endocrinology, 2020
We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu, Parvathy Madhavan, Lisa Chirch, Pooja Luthra   +3 more
doaj   +1 more source

Orbital lymphoma associated with Graves’ disease: A case report [PDF]

Vojnosanitetski Pregled, 2014
Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran, Kuzmić-Janković Snežana, Kljaković-Avramović Tamara, Sekulović Leposava, Tukić Ljiljana   +4 more
doaj   +1 more source

Aggravated Orbitopathy Following Remnant Ablation in a Patient with Multiple Cancers

Endocrinology Research and Practice, 2017
The rate of thyroid cancer in the patients with Graves’ disease is controversial. The rare incidents of multiple primary thyroid cancers in the same patient have been reported.
Umut MOUSA, Hasan SAV, Osman KÖSEOĞULLARI, Şebnem AYDIN, Hanife ÖZKAYALAR   +4 more
doaj   +1 more source

The change in the clinical presentation of Graves’ disease: a 30 years retrospective survey in an academic Brazilian tertiary center

Archives of Endocrinology and Metabolism, 2020
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto, João H. Romaldini, Nicolas Perini, Roberto B. Santos, Danilo Villagelin   +4 more
doaj   +1 more source

Isolated primary amyloidosis of the inferior rectus muscle mimicking Graves’ orbitopathy

Einstein (São Paulo)
The diagnosis of Graves’ orbitopathy is usually straightforward. However, orbital diseases that mimick some clinical signs of Graves’ orbitopathy may cause diagnostic confusion, particularly when associated to some form of thyroid dysfunction.
Mário Luiz Ribeiro Monteiro, Allan Christian Pieroni Gonçalves, Alanna Mara Pinheiro Sobreira Bezerra   +2 more
doaj   +1 more source

The relation between clinical response and quality of life improvement after treatment with intravenous methylprednisolone in Graves' orbitopathy

Acta Ophthalmologica, EarlyView.
Abstract Background Quality of life (QoL) is a key outcome in Graves' orbitopathy (GO), but prior studies have reported overall QoL changes without evaluating whether improvements occur specifically in patients who achieve objective clinical response.
Gijsbert J. Hötte, Willem A. Dik, Ronald O. B. de Keizer, Sodaba Khatab, M. Medici, Sigrid M. A. Swagemakers, Peter J. van der Spek, P. Martin van Hagen, Dion Paridaens   +8 more
wiley   +1 more source